PMID- 16041159
OWN - NLM
STAT- MEDLINE
DCOM- 20050929
LR  - 20220408
IS  - 1346-9843 (Print)
IS  - 1346-9843 (Linking)
VI  - 69
IP  - 8
DP  - 2005 Aug
TI  - Efficacy of nasal bi-level positive airway pressure in congestive heart failure 
      patients with cheyne-stokes respiration and central sleep apnea.
PG  - 913-21
AB  - BACKGROUND: Cheyne - Stokes respiration with central sleep apnea (CSR-CSA) 
      contributes to the poor prognosis in patients with congestive heart failure 
      (CHF). Bi-level positive airway pressure (bi-level PAP) may be an effective 
      alternative for treating CSR-CSA and CHF. METHODS AND RESULTS: Fourteen patients 
      with CSR-CSA were divided into 2 groups, a control group that included 7 patients 
      who decided to receive only conventional medications and a group of 7 patients 
      that received bi-level PAP. Left ventricular ejection fraction (LVEF), mitral 
      regurgitation (MR) area, plasma brain natriuretic peptide (BNP) concentration and 
      the New York Heart Association (NYHA) functional class were evaluated initially 
      (baseline) and 3 months later. In the control group, there were no significant 
      changes in cardiac function during the study period. In contrast, in the group 
      that received bi-level PAP, there were significant improvements in LVEF (from 
      36.3+/-2.9% to 46.0+/-4.0%, p = 0.02), MR area (from 30.4+/-7.6% to 20.0+/-5.1%, 
      p = 0.02), BNP (from 993.6+/-332.0 pg/ml to 474.0+/-257.6 pg/ml, p = 0.02) and 
      NYHA functional class (from 3.1+/-0.1 to 2.1+/-0.1, p = 0.03). CONCLUSION: 
      Treatment with bi-level PAP improved cardiac functions in CHF patients with 
      CSR-CSA.
FAU - Kasai, Takatoshi
AU  - Kasai T
AD  - Cardiovascular Center, Toranomon Hospital, Tokyo, Japan. kasai-t@mx6.nisiq.net
FAU - Narui, Koji
AU  - Narui K
FAU - Dohi, Tomotaka
AU  - Dohi T
FAU - Ishiwata, Sugao
AU  - Ishiwata S
FAU - Yoshimura, Kunihiko
AU  - Yoshimura K
FAU - Nishiyama, Shin-Ichiro
AU  - Nishiyama S
FAU - Yamaguchi, Tetsu
AU  - Yamaguchi T
FAU - Momomura, Shin-Ichi
AU  - Momomura S
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Japan
TA  - Circ J
JT  - Circulation journal : official journal of the Japanese Circulation Society
JID - 101137683
RN  - 114471-18-0 (Natriuretic Peptide, Brain)
SB  - IM
CIN - Circ J. 2005 Oct;69(10):1295; author reply 1296. PMID: 16200689
CIN - Circ J. 2006 Jun;70(6):802; author reply 803. PMID: 16755691
MH  - Aged
MH  - Aged, 80 and over
MH  - Cheyne-Stokes Respiration/blood/complications/*therapy
MH  - Female
MH  - Heart Failure/blood/complications/*therapy
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Natriuretic Peptide, Brain/blood
MH  - Nose
MH  - *Positive-Pressure Respiration
MH  - Sleep Apnea, Central/blood/complications/*therapy
MH  - Ventricular Function, Left
EDAT- 2005/07/26 09:00
MHDA- 2005/09/30 09:00
CRDT- 2005/07/26 09:00
PHST- 2005/07/26 09:00 [pubmed]
PHST- 2005/09/30 09:00 [medline]
PHST- 2005/07/26 09:00 [entrez]
AID - JST.JSTAGE/circj/69.913 [pii]
AID - 10.1253/circj.69.913 [doi]
PST - ppublish
SO  - Circ J. 2005 Aug;69(8):913-21. doi: 10.1253/circj.69.913.