PMID- 16044094
OWN - NLM
STAT- MEDLINE
DCOM- 20060425
LR  - 20190906
IS  - 0163-4356 (Print)
IS  - 0163-4356 (Linking)
VI  - 27
IP  - 4
DP  - 2005 Aug
TI  - 3,4-methylenedioxymethamphetamine (MDMA) intoxication in an infant chronically 
      exposed to cocaine.
PG  - 409-11
AB  - Accidental ingestion of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) was 
      detected in an infant admitted at the Pediatric Emergency Department by drug 
      testing in urine. Concentrations of MDMA and its principal metabolite 
      4-hydroxy-3-methoxymethamphetamine (HMMA) in the infant's hydrolyzed urine were 
      11.7 mg/L and 34.4 mg/L, respectively. Apparent febrile convulsions and 
      cardiovascular side effects resolved within 1 day after treatment with 
      benzodiazepines. Chronic exposure to cocaine was evidenced by segmental hair 
      analysis. Continuous maternal denial of the presence of any drug in the household 
      made diagnosis of accidental ingestion of MDMA and chronic exposure to cocaine 
      problematic. Periodic clinical and laboratory follow-ups were requested to check 
      eventual long-term effects of exposure to illicit drugs and discontinuation of 
      the child from exposure to dangerous environments.
FAU - Garcia-Algar, Oscar
AU  - Garcia-Algar O
AD  - Paediatric Service, Hospital del Mar, Barcelona, Spain. OGarciaA@imas.imim.es
FAU - Lopez, Nuria
AU  - Lopez N
FAU - Bonet, Mariona
AU  - Bonet M
FAU - Pellegrini, Manuela
AU  - Pellegrini M
FAU - Marchei, Emilia
AU  - Marchei E
FAU - Pichini, Simona
AU  - Pichini S
LA  - eng
PT  - Case Reports
PT  - Clinical Conference
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Ther Drug Monit
JT  - Therapeutic drug monitoring
JID - 7909660
RN  - 0 (Hallucinogens)
RN  - 0 (Lactates)
RN  - 12794-10-4 (Benzodiazepines)
RN  - 515-30-0 (atrolactic acid)
RN  - I5Y540LHVR (Cocaine)
RN  - KE1SEN21RM (N-Methyl-3,4-methylenedioxyamphetamine)
SB  - IM
MH  - Benzodiazepines/therapeutic use
MH  - Cocaine/analysis/*poisoning
MH  - Gas Chromatography-Mass Spectrometry/methods
MH  - Hair/chemistry
MH  - Hallucinogens/poisoning/urine
MH  - Humans
MH  - Infant
MH  - Lactates/urine
MH  - Male
MH  - N-Methyl-3,4-methylenedioxyamphetamine/*poisoning/urine
MH  - Seizures, Febrile/diagnosis/drug therapy
MH  - Substance Abuse Detection/methods
EDAT- 2005/07/27 09:00
MHDA- 2006/04/28 09:00
CRDT- 2005/07/27 09:00
PHST- 2005/07/27 09:00 [pubmed]
PHST- 2006/04/28 09:00 [medline]
PHST- 2005/07/27 09:00 [entrez]
AID - 00007691-200508000-00002 [pii]
AID - 10.1097/01.ftd.0000166041.97524.50 [doi]
PST - ppublish
SO  - Ther Drug Monit. 2005 Aug;27(4):409-11. doi: 10.1097/01.ftd.0000166041.97524.50.