PMID- 16045185
OWN - NLM
STAT- MEDLINE
DCOM- 20050830
LR  - 20110726
IS  - 0301-4894 (Print)
IS  - 0301-4894 (Linking)
VI  - 106
IP  - 7
DP  - 2005 Jul
TI  - [Treatment strategy for children with Wilms tumor].
PG  - 422-6
AB  - Wilms tumor has an excellent prognosis according to the findings of the National 
      Wilms Tumor Study (NWTS). The NWTS has been aiming to reduce the intensity of 
      treatment for low-risk groups. Pathologic assessment or statistical analysis has 
      identified the appropriate staging system suited to this treatment regimen. The 
      Japanese Wilms Tumor Study (JWiTS) has been following the NWTS-5 regimen to 
      increase survival rates and tumor-free survival rates from 1996. This study aims 
      to establish a central review system of pathology and to study the presence of 
      WT1 mutation in tumor samples. In addition, JWiTS focuses on developing an online 
      database that can be shared over the Internet. However, the prognosis in patients 
      with malignant rhabdoid tumor of the kidney (MRTK) is still poor. JWiTS has 
      started to consider a new regimen for MRTK.
FAU - Fukuzawa, Masahiro
AU  - Fukuzawa M
AD  - Division of Pediatric Surgery, Department of Surgery, Osaka University Graduate 
      School of Medicine, Osaka, Japan.
LA  - jpn
PT  - English Abstract
PT  - Journal Article
PT  - Review
PL  - Japan
TA  - Nihon Geka Gakkai Zasshi
JT  - Nihon Geka Gakkai zasshi
JID - 0405405
RN  - 0 (WT1 Proteins)
SB  - IM
MH  - Child
MH  - Chromosomes, Human, Pair 16/genetics
MH  - Combined Modality Therapy
MH  - Genes, Wilms Tumor
MH  - Humans
MH  - Kidney Neoplasms/diagnosis/genetics/pathology/*therapy
MH  - Loss of Heterozygosity
MH  - Mutation
MH  - Neoplasm Staging
MH  - Randomized Controlled Trials as Topic
MH  - Survival Rate
MH  - WT1 Proteins/genetics
MH  - Wilms Tumor/diagnosis/genetics/pathology/*therapy
RF  - 19
EDAT- 2005/07/28 09:00
MHDA- 2005/09/01 09:00
CRDT- 2005/07/28 09:00
PHST- 2005/07/28 09:00 [pubmed]
PHST- 2005/09/01 09:00 [medline]
PHST- 2005/07/28 09:00 [entrez]
PST - ppublish
SO  - Nihon Geka Gakkai Zasshi. 2005 Jul;106(7):422-6.