PMID- 16078036
OWN - NLM
STAT- MEDLINE
DCOM- 20060302
LR  - 20220330
IS  - 0939-5555 (Print)
IS  - 0939-5555 (Linking)
VI  - 84
IP  - 12
DP  - 2005 Nov
TI  - Randomized study of Helicobacter pylori eradication therapy and proton pump 
      inhibitor monotherapy for idiopathic thrombocytopenic purpura.
PG  - 807-11
AB  - Helicobacter pylori (HP) eradication therapy is a useful treatment for idiopathic 
      thrombocytopenic purpura (ITP). Some investigators have also reported the effects 
      of proton pump inhibitor (PPI) monotherapy on ITP. We performed a randomized 
      study of HP eradication therapy and PPI monotherapy on ITP. Four of nine patients 
      achieved complete remission (CR), two of nine achieved partial remission (PR) in 
      HP eradication therapy, three of eight achieved CR, and two of eight achieved PR 
      in PPI monotherapy. No significant differences were observed in the CR + PR of 
      these patients between HP eradication therapy and PPI monotherapy. As for cost 
      comparisons, HP eradication therapy is cheaper than PPI monotherapy, but it is 
      less effective.
FAU - Tsutsumi, Yutaka
AU  - Tsutsumi Y
AD  - Department of Internal Medicine, Hakodate Municipal Hospital, 1-10-1 Minato-Cho, 
      Hakodate, 041-8680, Japan. rtsutsu@nyc.odn.ne.jp
FAU - Kanamori, Hiroe
AU  - Kanamori H
FAU - Yamato, Hiroaki
AU  - Yamato H
FAU - Ehira, Nobuyuki
AU  - Ehira N
FAU - Kawamura, Takahito
AU  - Kawamura T
FAU - Umehara, Shintaro
AU  - Umehara S
FAU - Mori, Akio
AU  - Mori A
FAU - Obara, Shinji
AU  - Obara S
FAU - Ogura, Nobutaka
AU  - Ogura N
FAU - Tanaka, Junji
AU  - Tanaka J
FAU - Asaka, Masahiro
AU  - Asaka M
FAU - Imamura, Masahiro
AU  - Imamura M
FAU - Masauzi, Nobuo
AU  - Masauzi N
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
DEP - 20051112
PL  - Germany
TA  - Ann Hematol
JT  - Annals of hematology
JID - 9107334
RN  - 0 (2-Pyridinylmethylsulfinylbenzimidazoles)
RN  - 0 (Anti-Bacterial Agents)
RN  - 0 (Anti-Ulcer Agents)
RN  - 0 (Proton Pump Inhibitors)
RN  - 0K5C5T2QPG (Lansoprazole)
RN  - 804826J2HU (Amoxicillin)
RN  - H1250JIK0A (Clarithromycin)
RN  - KG60484QX9 (Omeprazole)
SB  - IM
CIN - Hepatology. 2006 Dec;44(6):1685-7. PMID: 17133476
MH  - 2-Pyridinylmethylsulfinylbenzimidazoles
MH  - Aged
MH  - Amoxicillin/*administration & dosage/economics
MH  - Anti-Bacterial Agents/*administration & dosage/economics
MH  - Anti-Ulcer Agents/*administration & dosage/economics
MH  - Clarithromycin/*administration & dosage/economics
MH  - Drug Therapy, Combination
MH  - Helicobacter Infections/complications/*drug therapy/economics/enzymology
MH  - *Helicobacter pylori
MH  - Humans
MH  - Lansoprazole
MH  - Male
MH  - Middle Aged
MH  - Omeprazole/administration & dosage/*analogs & derivatives/economics
MH  - Proton Pump Inhibitors
MH  - *Purpura, Thrombocytopenic, Idiopathic/complications/economics/enzymology
MH  - Remission Induction
MH  - Treatment Outcome
EDAT- 2005/08/04 09:00
MHDA- 2006/03/03 09:00
CRDT- 2005/08/04 09:00
PHST- 2005/02/14 00:00 [received]
PHST- 2005/05/11 00:00 [accepted]
PHST- 2005/08/04 09:00 [pubmed]
PHST- 2006/03/03 09:00 [medline]
PHST- 2005/08/04 09:00 [entrez]
AID - 10.1007/s00277-005-1071-z [doi]
PST - ppublish
SO  - Ann Hematol. 2005 Nov;84(12):807-11. doi: 10.1007/s00277-005-1071-z. Epub 2005 
      Nov 12.