PMID- 16081968 OWN - NLM STAT- MEDLINE DCOM- 20050915 LR - 20181113 IS - 0095-1137 (Print) IS - 1098-660X (Electronic) IS - 0095-1137 (Linking) VI - 43 IP - 8 DP - 2005 Aug TI - Prevalence of herpes simplex virus (types 1 and 2), varicella-zoster virus, cytomegalovirus, and human herpesvirus 6 and 7 DNA in cerebrospinal fluid of Middle Eastern patients with encephalitis. PG - 4172-4 AB - HSV-1 DNA was detected in 32 (30%) of 106 cerebrospinal fluid samples from patients with encephalitis. Cytomegalovirus, varicella-zoster virus, and human herpesvirus 6 (HHV-6) DNAs were each detected in three patients (3%); herpes simplex virus type 2 (HSV-2) and HHV-7 PCRs were negative. HSV detection was associated with seizure (P = 0.02), especially focal seizure (P = 0.0002), and pathological computed tomography (P = 0.02) with focal lesions (P = 0.0004). FAU - Ibrahim, Ali I AU - Ibrahim AI AD - Department of Clinical Chemistry and Microbiology, University of Damascus, Syria. FAU - Obeid, Michel T AU - Obeid MT FAU - Jouma, Muhidien J AU - Jouma MJ FAU - Roemer, Klaus AU - Roemer K FAU - Mueller-Lantzsch, Nikolaus AU - Mueller-Lantzsch N FAU - Gartner, Barbara C AU - Gartner BC LA - eng PT - Journal Article PL - United States TA - J Clin Microbiol JT - Journal of clinical microbiology JID - 7505564 RN - 0 (DNA, Viral) SB - IM MH - Adolescent MH - Adult MH - Child MH - Child, Preschool MH - Cytomegalovirus/genetics/isolation & purification MH - DNA, Viral/*cerebrospinal fluid MH - Encephalitis, Viral/cerebrospinal fluid/*virology MH - Female MH - Herpesviridae/*isolation & purification MH - Herpesvirus 1, Human/genetics/isolation & purification MH - Herpesvirus 2, Human/genetics/isolation & purification MH - Herpesvirus 3, Human/genetics/isolation & purification MH - Herpesvirus 6, Human/genetics/isolation & purification MH - Herpesvirus 7, Human/genetics/isolation & purification MH - Humans MH - Infant MH - Male PMC - PMC1233955 EDAT- 2005/08/06 09:00 MHDA- 2005/09/16 09:00 PMCR- 2006/02/01 CRDT- 2005/08/06 09:00 PHST- 2005/08/06 09:00 [pubmed] PHST- 2005/09/16 09:00 [medline] PHST- 2005/08/06 09:00 [entrez] PHST- 2006/02/01 00:00 [pmc-release] AID - 43/8/4172 [pii] AID - 0650-05 [pii] AID - 10.1128/JCM.43.8.4172-4174.2005 [doi] PST - ppublish SO - J Clin Microbiol. 2005 Aug;43(8):4172-4. doi: 10.1128/JCM.43.8.4172-4174.2005.