PMID- 16085750
OWN - NLM
STAT- MEDLINE
DCOM- 20051206
LR  - 20220408
IS  - 1469-0756 (Electronic)
IS  - 0032-5473 (Print)
IS  - 0032-5473 (Linking)
VI  - 81
IP  - 958
DP  - 2005 Aug
TI  - Acanthosis nigricans: relation with type 2 diabetes mellitus, anthropometric 
      variables, and body mass in Indians.
PG  - 541-4
AB  - OBJECTIVE: To determine the prevalence of acanthosis nigricans (AN) in type 2 
      diabetes mellitus (T2DM) and its correlation with various anthropometric 
      measurements in Indians. METHODS: One hundred and fifty consecutive subjects with 
      T2DM attending the diabetes clinic at a tertiary referral centre in North India 
      were considered as cases and 150 age and sex matched healthy attendants of 
      non-diabetic subjects as controls. All the cases and controls were screened for 
      the presence of AN and its severity. Anthropometric measurements of all of them 
      were measured in standard method. Regression analysis was done to determine the 
      association of AN with T2DM and various anthropometric measurements. RESULTS: The 
      prevalence of AN in subjects with diabetes and healthy controls was 62.6% and 40% 
      respectively, and this difference was significant (p<0.05). Body mass index (BMI) 
      between cases and controls was comparable by chance. There was a statistically 
      significant correlation of increasing severity of AN with increasing BMI, waist 
      circumference, hip circumference, waist-hip ratio, skinfold thickness, and body 
      fat percentage in diabetic patients. However, in regression analysis after 
      considering all the confounding factors there was a significant correlation of 
      AN, only with diabetes mellitus and BMI. CONCLUSIONS: Indians have high 
      prevalence of AN and it is an independent cutaneous marker of both T2DM and BMI.
FAU - Grandhe, N P
AU  - Grandhe NP
AD  - Department of Dermatology, Postgraduate Institute of Medical Education and 
      Research, Chandigarh, India.
FAU - Bhansali, A
AU  - Bhansali A
FAU - Dogra, S
AU  - Dogra S
FAU - Kumar, B
AU  - Kumar B
LA  - eng
PT  - Journal Article
PL  - England
TA  - Postgrad Med J
JT  - Postgraduate medical journal
JID - 0234135
SB  - IM
MH  - Acanthosis Nigricans/*complications/epidemiology/ethnology
MH  - Body Composition/physiology
MH  - Body Mass Index
MH  - Case-Control Studies
MH  - Diabetes Mellitus, Type 2/*complications/ethnology
MH  - Female
MH  - Humans
MH  - India/epidemiology/ethnology
MH  - Male
MH  - Middle Aged
MH  - Prevalence
PMC - PMC1743331
EDAT- 2005/08/09 09:00
MHDA- 2005/12/13 09:00
PMCR- 2008/08/01
CRDT- 2005/08/09 09:00
PHST- 2005/08/09 09:00 [pubmed]
PHST- 2005/12/13 09:00 [medline]
PHST- 2005/08/09 09:00 [entrez]
PHST- 2008/08/01 00:00 [pmc-release]
AID - 81/958/541 [pii]
AID - 10.1136/pgmj.2004.028308 [doi]
PST - ppublish
SO  - Postgrad Med J. 2005 Aug;81(958):541-4. doi: 10.1136/pgmj.2004.028308.