PMID- 16088763
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20051011
LR  - 20050809
IS  - 1069-3424 (Print)
IS  - 1069-3424 (Linking)
VI  - 21
IP  - 6
DP  - 2000
TI  - Treatment of acute deep venous thrombosis and pulmonary embolism: use of low 
      molecular weight heparin.
PG  - 547-53
AB  - Over the past decade, the use of low molecular weight heparin (LMWH) preparations 
      has revolutionized the approach to preventing and treating venous 
      thromboembolism. For established deep venous thrombosis, numerous prospective 
      clinical trials have indicated that these drugs are at least as safe and as 
      effective as standard, unfractionated heparin (UFH) and perhaps even more 
      effective at preventing recurrences. Advantages of low molecular weight heparin 
      include superior bioavailability compared with standard heparin, once- or 
      twice-daily subcutaneous delivery, and the lack of need to monitor in most 
      clinical circumstances. Because of these advantages, increasing numbers of 
      stable, compliant patients with deep venous thrombosis are being treated as 
      outpatients. This approach requires an organized team effort with comprehensive 
      patient education and carefully planned follow-up. Cost-benefit analyses have 
      unequivocally proved that when treatment with low molecular weight heparin is 
      utilized in the outpatient setting, there are substantial cost savings.
FAU - Tapson, V F
AU  - Tapson VF
AD  - Division of Pulmonary and Critical Care Medicine, Duke University Medical Center, 
      Durham, North Carolina 27710, USA. tapso001@mc.duke.edu
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Semin Respir Crit Care Med
JT  - Seminars in respiratory and critical care medicine
JID - 9431858
EDAT- 2005/08/10 09:00
MHDA- 2005/08/10 09:01
CRDT- 2005/08/10 09:00
PHST- 2005/08/10 09:00 [pubmed]
PHST- 2005/08/10 09:01 [medline]
PHST- 2005/08/10 09:00 [entrez]
AID - 10.1055/s-2000-13191 [doi]
PST - ppublish
SO  - Semin Respir Crit Care Med. 2000;21(6):547-53. doi: 10.1055/s-2000-13191.