PMID- 16094514
OWN - NLM
STAT- MEDLINE
DCOM- 20051209
LR  - 20181113
IS  - 1434-7229 (Print)
IS  - 1434-7229 (Linking)
VI  - 8
IP  - 2
DP  - 2005
TI  - QRS width does not reflect ventricular dyssynchrony in patients with heart 
      failure.
PG  - 100-3
AB  - The purpose of this study was to evaluate QRS width as an indication for cardiac 
      resynchronization therapy. This study group consisted of 64 heart failure 
      patients (51 men, age average 60.5 +/- 15.5 years) with a left ventricular 
      ejection fraction (LVEF) of less than 35%. Patients were divided into two groups 
      according to their QRS width; the wide QRS group (QRS width greater than or equal 
      to 120 ms, 31 patients) and the narrow QRS group (QRS width less than 120 ms, 33 
      patients). The ventricular dyssynchrony (VD), i.e., the inter- and 
      intraventricular dyssynchrony, of the two groups was compared. The correlation 
      between QRS width and VD was evaluated in all patients. There were no significant 
      differences between the wide and the narrow QRS groups concerning 
      interventricular dyssynchrony [28.4 +/- 26.1 ms vs. 25.3 +/- 18.2 ms, not 
      significant (NS)] or intraventricular dyssynchrony (99.0 +/- 43.8 ms vs. 109.0 
      +/- 56.6 ms, NS). Nor were there any differences in the LVEF (26.6 +/- 6.6% vs. 
      28.2 +/- 5.1%, NS), brain natriuretic peptide (BNP) (567.0 +/- 319.0 pg/ml vs. 
      390.0 +/- 375.8 pg/ml, NS), and New York Heart Association (NYHA) class (2.4 +/- 
      0.8 vs. 2.0 +/- 1.0, NS). QRS width did not correlate with interventricular (r = 
      0.026, NS) or intraventricular dyssynchrony (r = 0.052, NS). There were no 
      differences in VD between the two groups based on differences in QRS width. There 
      was also no correlation between QRS width and VD. It is suggested that QRS width 
      is not an absolute indication for cardiac resynchronization therapy.
FAU - Uchiyama, Tomoe
AU  - Uchiyama T
AD  - Division of Cardiology, Department of Internal Medicine, Saitama Medical School, 
      Iruma-gun, Saitama 350-0495, Japan.
FAU - Matsumoto, Kazuo
AU  - Matsumoto K
FAU - Suga, Chikashi
AU  - Suga C
FAU - Kato, Ritsushi
AU  - Kato R
FAU - Nishimura, Shigeyuki
AU  - Nishimura S
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - Japan
TA  - J Artif Organs
JT  - Journal of artificial organs : the official journal of the Japanese Society for 
      Artificial Organs
JID - 9815648
SB  - IM
MH  - Aged
MH  - Bundle-Branch Block/physiopathology/therapy
MH  - Cardiac Pacing, Artificial/methods
MH  - *Electrocardiography
MH  - Evaluation Studies as Topic
MH  - Female
MH  - Heart Conduction System/*physiopathology
MH  - Heart Failure/*physiopathology/*therapy
MH  - Heart Ventricles/physiopathology
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Predictive Value of Tests
MH  - Retrospective Studies
MH  - Treatment Outcome
EDAT- 2005/08/12 09:00
MHDA- 2005/12/13 09:00
CRDT- 2005/08/12 09:00
PHST- 2004/09/17 00:00 [received]
PHST- 2005/03/11 00:00 [accepted]
PHST- 2005/08/12 09:00 [pubmed]
PHST- 2005/12/13 09:00 [medline]
PHST- 2005/08/12 09:00 [entrez]
AID - 10.1007/s10047-005-0287-y [doi]
PST - ppublish
SO  - J Artif Organs. 2005;8(2):100-3. doi: 10.1007/s10047-005-0287-y.