PMID- 16104630
OWN - NLM
STAT- MEDLINE
DCOM- 20051207
LR  - 20191210
IS  - 1027-3719 (Print)
IS  - 1027-3719 (Linking)
VI  - 9
IP  - 8
DP  - 2005 Aug
TI  - Comparison of erythema and induration as results of tuberculin tests.
PG  - 853-7
AB  - SETTING: Schoolchildren, tuberculosis (TB) patients, and hospital employees in 
      Tokyo, Japan. OBJECTIVE: To compare erythema and induration resulting from 
      tuberculin tests among TB patients, normal children, and hospital employees with 
      and without evidence of atopy. DESIGN: The distributions of diameters of erythema 
      and induration were compared among three groups: 951 TB patients, 6139 
      first-grade and 6185 seventh-grade children, and 97 volunteer employees 
      classified as atopic or non-atopic on the basis of skin tests and serum 
      immunoglobulin E (IgE) concentrations. RESULTS: Erythema and induration were 
      highly correlated. The distribution of erythema diameters was unimodal, and the 
      distribution of induration diameters was bimodal. Erythema was considerably 
      greater than induration among persons classified as being atopic. CONCLUSION: 
      Both erythema and induration appear to be adequate indices of tuberculin 
      sensitivity. However, because most of the world uses induration as the index and 
      virtually all studies of tuberculin sensitivity rely on induration, there are 
      advantages in the use of induration. It would be desirable to initiate a large 
      prospective study to see whether erythema or induration is the better predictor 
      of subsequent tuberculous disease, and to confirm our finding that erythema is 
      more likely to be confounded by atopy than induration.
FAU - Kimura, M
AU  - Kimura M
AD  - Ministry of Health, Labor, and Welfare, Tokyo, Japan.
FAU - Comstock, G W
AU  - Comstock GW
FAU - Mori, T
AU  - Mori T
LA  - eng
PT  - Comparative Study
PT  - Evaluation Study
PT  - Journal Article
PL  - France
TA  - Int J Tuberc Lung Dis
JT  - The international journal of tuberculosis and lung disease : the official journal 
      of the International Union against Tuberculosis and Lung Disease
JID - 9706389
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
CIN - Int J Tuberc Lung Dis. 2006 Feb;10(2):125-32. PMID: 16499249
MH  - Adult
MH  - Aged
MH  - Child
MH  - Erythema/*chemically induced
MH  - Female
MH  - Humans
MH  - Hypersensitivity, Immediate
MH  - Immunoglobulin E/blood
MH  - Male
MH  - Middle Aged
MH  - Personnel, Hospital
MH  - Reference Values
MH  - Sensitivity and Specificity
MH  - Tuberculin Test/*standards
MH  - Tuberculosis/*diagnosis
EDAT- 2005/08/18 09:00
MHDA- 2005/12/13 09:00
CRDT- 2005/08/18 09:00
PHST- 2005/08/18 09:00 [pubmed]
PHST- 2005/12/13 09:00 [medline]
PHST- 2005/08/18 09:00 [entrez]
PST - ppublish
SO  - Int J Tuberc Lung Dis. 2005 Aug;9(8):853-7.