PMID- 16105557
OWN - NLM
STAT- MEDLINE
DCOM- 20051209
LR  - 20050817
IS  - 0037-1963 (Print)
IS  - 0037-1963 (Linking)
VI  - 42
IP  - 3 Suppl 3
DP  - 2005 Jul
TI  - The incidence and clinical features of heparin-induced thrombocytopenia.
PG  - S3-8
AB  - Heparin-induced thrombocytopenia (HIT) is an important adverse reaction of 
      heparin therapy that can have catastrophic consequences if overlooked or 
      misdiagnosed. Treatment with either unfractionated heparin (UFH) or 
      low-molecular-weight heparin (LMWH) can trigger this complication. Orthopedic, 
      cardiac, and vascular surgery patients exposed to prophylactic or therapeutic 
      doses of heparin are at particular risk. Awareness of the clinical features and 
      different presentations of HIT are essential for preventing severe morbidity and 
      mortality associated with this disease.
FAU - Bartholomew, John R
AU  - Bartholomew JR
AD  - Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, OH 
      44195, USA. barthoj@ccf.org
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Semin Hematol
JT  - Seminars in hematology
JID - 0404514
RN  - 0 (Anticoagulants)
RN  - 0 (Heparin, Low-Molecular-Weight)
SB  - IM
MH  - Anticoagulants/administration & dosage/*adverse effects
MH  - Heparin, Low-Molecular-Weight/administration & dosage/*adverse effects
MH  - Humans
MH  - Incidence
MH  - Surgical Procedures, Operative
MH  - Thrombocytopenia/chemically induced/mortality/*pathology
RF  - 24
EDAT- 2005/08/18 09:00
MHDA- 2005/12/13 09:00
CRDT- 2005/08/18 09:00
PHST- 2005/08/18 09:00 [pubmed]
PHST- 2005/12/13 09:00 [medline]
PHST- 2005/08/18 09:00 [entrez]
AID - S0037-1963(05)00072-7 [pii]
AID - 10.1053/j.seminhematol.2005.05.012 [doi]
PST - ppublish
SO  - Semin Hematol. 2005 Jul;42(3 Suppl 3):S3-8. doi: 
      10.1053/j.seminhematol.2005.05.012.