PMID- 16110687
OWN - NLM
STAT- MEDLINE
DCOM- 20051025
LR  - 20131121
IS  - 0095-6562 (Print)
IS  - 0095-6562 (Linking)
VI  - 76
IP  - 8
DP  - 2005 Aug
TI  - Leukocyte subset responses during exercise under heat stress with carbohydrate or 
      water intake.
PG  - 726-32
AB  - PURPOSE: This study investigated leukocyte subset responses to moderate-intensity 
      exercise under heat stress, with water (W) or carbohydrate (CHO) drink ingestion. 
      METHODS: In repeated trials, 13 soldiers consumed either a W or CHO drink during 
      3 h of walking at 4.4 km x h(-1) with a 5% gradient (15 min rest per hour) under 
      heat stress (35 degrees C and 55% relative humidity). The soldiers wore combat 
      uniforms and carried water bottles and dummy rifles and ammunition, altogether 
      weighing about 11.5 +/- 1.0 kg. RESULTS: Plasma glucose concentration was 
      significantly higher with CHO than W ingestion during exercise (p < 0.01). There 
      were no significant differences between W and CHO conditions in exercise 
      performance, plasma cortisol concentration, heart rate, or core temperature. CHO 
      ingestion significantly moderated the increases in leukocyte (83% in W, 28% in 
      CHO; p < 0.001), monocyte (60% in W, 34% in CHO; p < 0.05), and granulocyte 
      counts (120% in W, 30% in CHO; p < 0.001), but not in lymphocyte count (41% in W, 
      25% in CHO). CONCLUSIONS: The increases in leukocyte and subset counts during 
      moderate-intensity exercise under heat stress may be comparable to those observed 
      during intense exercise in cool conditions. The response of immune cell counts is 
      blunted by CHO intake during moderate-intensity exercise in the heat, and may not 
      occur through the cortisol pathway.
FAU - Lim, Chin Leong
AU  - Lim CL
AD  - Military Physiology Laboratory, Defence Medical and Environmental Research, DSO 
      National Laboratories, 27 Medical Drive, #09-01, Singapore 117510, Republic of 
      Singapore. limcl@dso.org.sg
FAU - Byrne, Christopher
AU  - Byrne C
FAU - Chew, Serena A N
AU  - Chew SA
FAU - Mackinnon, Laurel T
AU  - Mackinnon LT
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Aviat Space Environ Med
JT  - Aviation, space, and environmental medicine
JID - 7501714
RN  - 0 (Blood Glucose)
RN  - 0 (Dietary Carbohydrates)
RN  - 059QF0KO0R (Water)
RN  - WI4X0X7BPJ (Hydrocortisone)
SB  - IM
MH  - Adult
MH  - Blood Glucose
MH  - Dietary Carbohydrates
MH  - Drinking Behavior
MH  - Exercise/*physiology
MH  - Heart Rate
MH  - *Heat Stress Disorders
MH  - Humans
MH  - Hydrocortisone/blood
MH  - Leukocytes/*physiology
MH  - Male
MH  - Water
EDAT- 2005/08/23 09:00
MHDA- 2005/10/26 09:00
CRDT- 2005/08/23 09:00
PHST- 2005/08/23 09:00 [pubmed]
PHST- 2005/10/26 09:00 [medline]
PHST- 2005/08/23 09:00 [entrez]
PST - ppublish
SO  - Aviat Space Environ Med. 2005 Aug;76(8):726-32.