PMID- 1611536
OWN - NLM
STAT- MEDLINE
DCOM- 19920724
LR  - 20190613
IS  - 0006-8993 (Print)
IS  - 0006-8993 (Linking)
VI  - 572
IP  - 1-2
DP  - 1992 Feb 14
TI  - c-fos may code for a common transcription factor within the hypothalamic neural 
      circuits involved in osmoregulation.
PG  - 42-51
AB  - Conscious rats were given an intraperitoneal (i.p.) injection of isotonic or 
      hypertonic saline, and killed 10-240 min later. In the hypothalamus of hypertonic 
      saline-injected rats, c-fos-mRNA positive cells were mainly restricted to the 
      supraoptic and paraventricular nuclei and to structures associated with the 
      lamina terminalis of the third ventricle, including in particular the subfornical 
      organ, the organum vasculosum of the lamina terminalis (OVLT) and the median 
      preoptic nucleus. These structures comprise the proposed anterior hypothalamic 
      'osmoreceptor complex' for regulation of vasopressin release. The time course of 
      the appearance and disappearance of c-fos mRNA signals was similar in all 
      regions. Thus c-fos protein (Fos) may be a common transcription factor in the 
      hypothalamic neural circuits involved in osmoregulation.
FAU - Hamamura, M
AU  - Hamamura M
AD  - Department of Neuroendocrinology, AFRC Institute of Animal Physiology and 
      Genetics Research, Babraham, U.K.
FAU - Nunez, D J
AU  - Nunez DJ
FAU - Leng, G
AU  - Leng G
FAU - Emson, P C
AU  - Emson PC
FAU - Kiyama, H
AU  - Kiyama H
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Netherlands
TA  - Brain Res
JT  - Brain research
JID - 0045503
RN  - 0 (RNA, Messenger)
RN  - 0 (Saline Solution, Hypertonic)
RN  - 0 (Transcription Factors)
SB  - IM
GS  - c-fos
MH  - Animals
MH  - Cerebral Ventricles/metabolism
MH  - Genes, fos/*genetics
MH  - Hypothalamus/*physiology
MH  - Male
MH  - Neural Pathways/physiology
MH  - Paraventricular Hypothalamic Nucleus/metabolism
MH  - RNA, Messenger/*biosynthesis
MH  - Rats
MH  - Rats, Inbred Strains
MH  - Saline Solution, Hypertonic
MH  - Supraoptic Nucleus/metabolism
MH  - Transcription Factors/*genetics
MH  - Water-Electrolyte Balance/*physiology
EDAT- 1992/02/14 00:00
MHDA- 1992/02/14 00:01
CRDT- 1992/02/14 00:00
PHST- 1992/02/14 00:00 [pubmed]
PHST- 1992/02/14 00:01 [medline]
PHST- 1992/02/14 00:00 [entrez]
AID - 0006-8993(92)90448-I [pii]
AID - 10.1016/0006-8993(92)90448-i [doi]
PST - ppublish
SO  - Brain Res. 1992 Feb 14;572(1-2):42-51. doi: 10.1016/0006-8993(92)90448-i.