PMID- 16130463
OWN - NLM
STAT- MEDLINE
DCOM- 20051223
LR  - 20191109
IS  - 0931-2668 (Print)
IS  - 0931-2668 (Linking)
VI  - 122 Suppl 1
DP  - 2005 Apr
TI  - Comparative chromosomal studies of E. caballus (ECA) and E. przewalskii (EPR) in 
      a female F1 hybrid.
PG  - 97-102
AB  - Previous research revealed that the karyotypes of Equus przewalskii (2n = 66) and 
      Equus caballus (2n = 64) differ by one pair of metacentric chromosomes, present 
      in ECA but not in EPR, and two pairs of acrocentric chromosomes found only in the 
      EPR karyotype. The formation of a trivalent during meiosis in a male F1 hybrid 
      and the homologies in G-banding patterns suggest that ECA 5 corresponds to two 
      acrocentric EPR chromosomes resulting from a Robertsonian fusion or fission 
      event. Chromosomal investigations of a female interspecies F1 hybrid including 
      banded karyograms and fluorescence in situ hybridization (FISH) studies focusing 
      on the p and q arm of ECA 5 were conducted. Q- and G-banding patterns of E. 
      caballus, E. przewalskii and the hybrid revealed interspecies homology between 
      all chromosome pairs except for ECA 5, EPR 23 and EPR 24, which were unique for 
      that particular species. Furthermore, they indicated homology between ECA 5p and 
      EPR 23 as well as between ECA 5q and EPR 24. FISH revealed hybridization of the 
      BACs laminin beta 3 (LAM B3) and laminin gamma 2 (LAM C2) to ECA 5p and EPR 23. 
      However, nuclear factor I (NFIA) and immunoglobulin lambda (IGL@), primarily 
      assigned to ECA 5q, mapped to ECA 7 and EPR 6 respectively. Thus the karyotypes 
      of E. caballus and E. przewalskii differ solely by one Robertsonian translocation 
      (ECA 5 =EPR 23 + EPR 24).
FAU - Ahrens, E
AU  - Ahrens E
AD  - Department of Animal Sciences, Swiss Federal Institute of Technology, Zurich, 
      Switzerland.
FAU - Stranzinger, G
AU  - Stranzinger G
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Germany
TA  - J Anim Breed Genet
JT  - Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und 
      Zuchtungsbiologie
JID - 100955807
SB  - IM
MH  - Animals
MH  - Chromosomes, Mammalian/*genetics
MH  - Female
MH  - Horses/*genetics
MH  - Hybridization, Genetic/*genetics
MH  - In Situ Hybridization, Fluorescence/veterinary
MH  - Karyotyping/veterinary
MH  - Species Specificity
MH  - Translocation, Genetic/genetics
EDAT- 2005/09/01 09:00
MHDA- 2005/12/24 09:00
CRDT- 2005/09/01 09:00
PHST- 2005/09/01 09:00 [pubmed]
PHST- 2005/12/24 09:00 [medline]
PHST- 2005/09/01 09:00 [entrez]
AID - 10.1111/j.1439-0388.2005.00494.x [doi]
PST - ppublish
SO  - J Anim Breed Genet. 2005 Apr;122 Suppl 1:97-102. doi: 
      10.1111/j.1439-0388.2005.00494.x.