PMID- 16131695
OWN - NLM
STAT- MEDLINE
DCOM- 20051003
LR  - 20220316
IS  - 1526-484X (Print)
IS  - 1526-484X (Linking)
VI  - 15
IP  - 3
DP  - 2005 Jun
TI  - Accuracy of urine specific gravity and osmolality as indicators of hydration 
      status.
PG  - 236-51
AB  - To reduce the adverse consequences of exertion-related and acute intentional 
      dehydration research has focused on monitoring hydration status. This 
      investigation: 1) compared sensitivity of urine specific gravity (Usg), urine 
      osmolality (U(osm)) and a criterion measurement of hydration, plasma osmolality 
      (P(osm)), at progressive stages of acute hypertonic dehydration and 2) using a 
      medical decision model, determined whether Usg or U(osm) accurately reflected 
      hydration status compared to P(osm) among 51 subjects tested throughout the day. 
      Incremental changes in P(osm) were observed as subjects dehydrated by 5% of body 
      weight and rehydrated while Usg and U(osm) showed delayed dehydration-related 
      changes. Using the medical decision model, sensitivity and specificity were not 
      significant at selected cut-offs for Usg and U(osm). At the most accurate cut-off 
      values, 1.015 and 1.020 for Usg and 700 m(osm)/kg and 800 m(osm)/kg for U(osm), 
      only 65% of the athletes were correctly classified using Usg and 63% using 
      U(osm). P(osm), Usg, and U(osm) appear sensitive to incremental changes in acute 
      hypertonic dehydration, however, the misclassified outcomes for Usg and U(osm) 
      raise concerns. Research focused on elucidating the factors affecting accurate 
      assessment of hydration status appears warranted.
FAU - Oppliger, Robert A
AU  - Oppliger RA
AD  - Iowa Wrestling Research, Iowa City, IA 52240, USA.
FAU - Magnes, Scott A
AU  - Magnes SA
FAU - Popowski, LeRoy A
AU  - Popowski LA
FAU - Gisolfi, Carl V
AU  - Gisolfi CV
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Int J Sport Nutr Exerc Metab
JT  - International journal of sport nutrition and exercise metabolism
JID - 100939812
RN  - 0 (Biomarkers)
SB  - IM
MH  - Adult
MH  - Analysis of Variance
MH  - Biomarkers/*urine
MH  - Dehydration/diagnosis/*urine
MH  - Exercise/*physiology
MH  - Humans
MH  - Male
MH  - Osmolar Concentration
MH  - Reference Values
MH  - Sensitivity and Specificity
MH  - Specific Gravity
MH  - Urine/*chemistry
MH  - Water-Electrolyte Balance/*physiology
EDAT- 2005/09/01 09:00
MHDA- 2005/10/04 09:00
CRDT- 2005/09/01 09:00
PHST- 2005/09/01 09:00 [pubmed]
PHST- 2005/10/04 09:00 [medline]
PHST- 2005/09/01 09:00 [entrez]
AID - 10.1123/ijsnem.15.3.236 [doi]
PST - ppublish
SO  - Int J Sport Nutr Exerc Metab. 2005 Jun;15(3):236-51. doi: 
      10.1123/ijsnem.15.3.236.