PMID- 16136891
OWN - NLM
STAT- MEDLINE
DCOM- 20100514
LR  - 20181201
IS  - 0529-567X (Print)
IS  - 0529-567X (Linking)
VI  - 36
IP  - 12
DP  - 2001 Dec
TI  - [Study on the correlation of the cytokine secreted by the endometrium focus and 
      the microenvironment of the fleument fluid].
PG  - 723-6
AB  - OBJECTIVE: To investigate the correlation of endometriotic focus and peritoneal 
      fluid as well as its effect on reproduction. METHODS: Forty-three women with 
      surgical treatment or laproscope with infertility are divided into endometriosis 
      group (24 cases) and normal pelvic group (control group 19 cases) . The 
      pathophysiology of patient' s peritoneal fluid, celiac macrophages and 
      endometriotic cells are analyzed by chemotactic test on monocytes, dot blot 
      hybridize, enzyme linked immunoadsorbent assay and the level of cytoplasmic 
      [Ca2+]i respectively. Meanwhile, the influence of peritoneal fluid and 
      endometriotic cells to sperm motivity as well as the effects to rat embryo 
      cleavage are evaluated. RESULTS: The monocyte moving distance induced by 
      peritoneal fluid in endometriosis group vs. control is (87.2 +/- 9.4) m vs. (51.9 
      +/- 3.7) microm (P < 0.01). The count of celiac macrophages (1.47 +/- 0.87) x 
      10(6)/ml vs. (0.67 +/- 0.73) x 10(6)/ml (P < 0.01), The basic expression level of 
      monocyte chamotactic protein-1 (MCP-1) in endometriotic cells is (18.34 +/- 3.95) 
      A. After exposured to IL-1beta and tumor necrosis factor-alpha, the OD of 
      MCP-lmRNA is 56.84 +/- 3.21 A and 41.58 +/- 2.48 A respectively (P < 0.01 ). 
      CONCLUSION: With the influence between endometriotic focus and microenvironment 
      of peritoneal fluid, the level of cytokines expressed by celiac macrophages and 
      endometriotic focus are enhanced, and it can interfere some process in 
      reproduction.
FAU - Gao, Y
AU  - Gao Y
AD  - Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, 
      Huazhong University of Scientific and Technology, Wuhan 430030, China.
FAU - Liu, Y
AU  - Liu Y
FAU - Luo, L
AU  - Luo L
LA  - chi
PT  - Journal Article
PL  - China
TA  - Zhonghua Fu Chan Ke Za Zhi
JT  - Zhonghua fu chan ke za zhi
JID - 16210370R
RN  - 0 (Chemokine CCL2)
RN  - 0 (Cytokines)
SB  - IM
MH  - Animals
MH  - Ascitic Fluid/*physiology
MH  - Case-Control Studies
MH  - Chemokine CCL2/genetics/*metabolism
MH  - Cytokines/*metabolism
MH  - Endometriosis/*physiopathology
MH  - Endometrium/*cytology/metabolism
MH  - Enzyme-Linked Immunosorbent Assay
MH  - Female
MH  - Humans
MH  - Macrophages/*physiology
MH  - Rats
MH  - Reproduction/physiology
MH  - Sperm Motility
EDAT- 2005/09/03 09:00
MHDA- 2010/05/15 06:00
CRDT- 2005/09/03 09:00
PHST- 2005/09/03 09:00 [pubmed]
PHST- 2010/05/15 06:00 [medline]
PHST- 2005/09/03 09:00 [entrez]
PST - ppublish
SO  - Zhonghua Fu Chan Ke Za Zhi. 2001 Dec;36(12):723-6.