PMID- 16143604
OWN - NLM
STAT- MEDLINE
DCOM- 20061006
LR  - 20240322
IS  - 0016-6731 (Print)
IS  - 0016-6731 (Linking)
VI  - 171
IP  - 4
DP  - 2005 Dec
TI  - Comprehensive molecular cytogenetic analysis of sorghum genome architecture: 
      distribution of euchromatin, heterochromatin, genes and recombination in 
      comparison to rice.
PG  - 1963-76
AB  - Cytogenetic maps of sorghum chromosomes 3-7, 9, and 10 were constructed on the 
      basis of the fluorescence in situ hybridization (FISH) of approximately 18-30 BAC 
      probes mapped across each of these chromosomes. Distal regions of euchromatin and 
      pericentromeric regions of heterochromatin were delimited for all 10 sorghum 
      chromosomes and their DNA content quantified. Euchromatic DNA spans approximately 
      50% of the sorghum genome, ranging from approximately 60% of chromosome 1 
      (SBI-01) to approximately 33% of chromosome 7 (SBI-07). This portion of the 
      sorghum genome is predicted to encode approximately 70% of the sorghum genes ( 
      approximately 1 gene model/12.3 kbp), assuming that rice and sorghum encode a 
      similar number of genes. Heterochromatin spans approximately 411 Mbp of the 
      sorghum genome, a region characterized by a approximately 34-fold lower rate of 
      recombination and approximately 3-fold lower gene density compared to euchromatic 
      DNA. The sorghum and rice genomes exhibit a high degree of macrocolinearity; 
      however, the sorghum genome is approximately 2-fold larger than the rice genome. 
      The distal euchromatic regions of sorghum chromosomes 3-7 and 10 are 
      approximately 1.8-fold larger overall and exhibit an approximately 1.5-fold lower 
      average rate of recombination than the colinear regions of the homeologous rice 
      chromosomes. By contrast, the pericentromeric heterochromatic regions of these 
      chromosomes are on average approximately 3.6-fold larger in sorghum and 
      recombination is suppressed approximately 15-fold compared to the colinear 
      regions of rice chromosomes.
FAU - Kim, J-S
AU  - Kim JS
AD  - Department of Biochemistry and Biophysics, Texas A&M University, College Station, 
      TX 77843, USA.
FAU - Islam-Faridi, M N
AU  - Islam-Faridi MN
FAU - Klein, P E
AU  - Klein PE
FAU - Stelly, D M
AU  - Stelly DM
FAU - Price, H J
AU  - Price HJ
FAU - Klein, R R
AU  - Klein RR
FAU - Mullet, J E
AU  - Mullet JE
LA  - eng
SI  - GENBANK/CZ682513
SI  - GENBANK/CZ682514
SI  - GENBANK/CZ682515
SI  - GENBANK/CZ682516
SI  - GENBANK/CZ682517
SI  - GENBANK/CZ682518
SI  - GENBANK/CZ682519
SI  - GENBANK/CZ682520
SI  - GENBANK/CZ682521
SI  - GENBANK/CZ682522
SI  - GENBANK/CZ682523
SI  - GENBANK/CZ682524
SI  - GENBANK/CZ682525
SI  - GENBANK/CZ682526
SI  - GENBANK/CZ682527
SI  - GENBANK/CZ682528
SI  - GENBANK/CZ682529
SI  - GENBANK/CZ682530
SI  - GENBANK/CZ682531
SI  - GENBANK/CZ682532
SI  - GENBANK/CZ682533
SI  - GENBANK/CZ682534
SI  - GENBANK/CZ682535
SI  - GENBANK/CZ682536
SI  - GENBANK/CZ682537
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, U.S. Gov't, Non-P.H.S.
DEP - 20050902
PL  - United States
TA  - Genetics
JT  - Genetics
JID - 0374636
RN  - 0 (Euchromatin)
RN  - 0 (Heterochromatin)
SB  - IM
MH  - Base Sequence
MH  - Chromosome Mapping
MH  - Chromosomes, Artificial, Bacterial
MH  - Euchromatin/*genetics
MH  - Genes, Plant/*genetics
MH  - Genome, Plant/*genetics
MH  - Genomics/methods
MH  - Heterochromatin/*genetics
MH  - In Situ Hybridization, Fluorescence
MH  - Molecular Sequence Data
MH  - Oryza/*genetics
MH  - Recombination, Genetic/*genetics
MH  - Sequence Analysis, DNA
MH  - Sorghum/*genetics
MH  - Species Specificity
PMC - PMC1456119
EDAT- 2005/09/07 09:00
MHDA- 2006/10/07 09:00
PMCR- 2006/03/01
CRDT- 2005/09/07 09:00
PHST- 2005/09/07 09:00 [pubmed]
PHST- 2006/10/07 09:00 [medline]
PHST- 2005/09/07 09:00 [entrez]
PHST- 2006/03/01 00:00 [pmc-release]
AID - genetics.105.048215 [pii]
AID - gen17141963 [pii]
AID - 10.1534/genetics.105.048215 [doi]
PST - ppublish
SO  - Genetics. 2005 Dec;171(4):1963-76. doi: 10.1534/genetics.105.048215. Epub 2005 
      Sep 2.