PMID- 16150402
OWN - NLM
STAT- MEDLINE
DCOM- 20051220
LR  - 20050909
IS  - 1521-6942 (Print)
IS  - 1521-6942 (Linking)
VI  - 19
IP  - 5
DP  - 2005 Oct
TI  - Management of "refractory" skin disease in patients with lupus erythematosus.
PG  - 767-84
AB  - Skin disease in patients with lupus erythematosus can be subdivided into two 
      broad categories-those lesions that, when biopsied, demonstrate an interface 
      dermatitis and those that do not demonstrate an interface dermatitis. The skin 
      lesions that are represented by the interface dermatitis include discoid lupus 
      erythematosus (DLE), subacute cutaneous lupus erythematosus (SCLE), and acute 
      cutaneous lupus erythematosus. Many patients with these cutaneous lesions can be 
      managed with "standard" therapies, including sunscreens, protective clothing and 
      behavioral alteration, and topical corticosteroids with or without an oral 
      antimalarial agent. These standard therapies are often not used appropriately, 
      resulting in a situation in which the patient is felt to have refractory disease. 
      This chapter discusses these therapies and defines what is meant by refractory 
      disease and how the author approaches these patients.
FAU - Callen, Jeffrey P
AU  - Callen JP
AD  - Division of Dermatology, School of Medicine, University of Louisville, 310 East 
      Broadway, Louisville, KY 40202, USA. jefca@aol.com
LA  - eng
PT  - Journal Article
PT  - Review
PL  - Netherlands
TA  - Best Pract Res Clin Rheumatol
JT  - Best practice & research. Clinical rheumatology
JID - 101121149
RN  - 0 (Antimalarials)
RN  - 0 (Glucocorticoids)
RN  - 0 (Sunscreening Agents)
SB  - IM
MH  - Antimalarials/administration & dosage/*therapeutic use
MH  - Diagnosis, Differential
MH  - Drug Administration Routes
MH  - Glucocorticoids/administration & dosage/*therapeutic use
MH  - Humans
MH  - Lupus Erythematosus, Cutaneous/diagnosis/*drug therapy
MH  - Sunscreening Agents/*therapeutic use
MH  - Treatment Outcome
RF  - 78
EDAT- 2005/09/10 09:00
MHDA- 2005/12/21 09:00
CRDT- 2005/09/10 09:00
PHST- 2005/09/10 09:00 [pubmed]
PHST- 2005/12/21 09:00 [medline]
PHST- 2005/09/10 09:00 [entrez]
AID - S1521-6942(05)00050-1 [pii]
AID - 10.1016/j.berh.2005.05.003 [doi]
PST - ppublish
SO  - Best Pract Res Clin Rheumatol. 2005 Oct;19(5):767-84. doi: 
      10.1016/j.berh.2005.05.003.