PMID- 16153516 OWN - NLM STAT- MEDLINE DCOM- 20060411 LR - 20161124 IS - 1097-6795 (Electronic) IS - 0894-7317 (Linking) VI - 18 IP - 9 DP - 2005 Sep TI - Atrial function after surgical and percutaneous closure of atrial septal defect: a strain rate imaging study. PG - 930-3 AB - The effect of operation and the effect of the imposition of an occluding device on atrial function for patients with an atrial septal defect (ASD) has never been studied. Thus, the aim of this study was to evaluate for the first time both left atrial (LA) and right atrial (RA) function of children after transcatheter ASD closure with that of sex- and age-matched patients with surgically treated ASD, and sex- and age-matched control subjects using strain (epsilon) and epsilon rate imaging (SR). In all, 45 participants formed our studied sample: 15 patients after successful ASD device closure (ASD-D [atrial septal defect device closure] group, mean age: 9 +/- 3 years) and 15 age- and sex-matched patients after successful ASD surgical closure (ASD-S [atrial septal defect surgical closure] group, mean age: 9 +/- 3 years). All patients underwent ASD correction at least 6 months before the study. As a control group we selected 15 age- and sex-matched control subjects. In the ASD-S group the peak systolic epsilon and SR values were significantly reduced in both RA and LA when compared with control and ASD-D groups (P < .01). In the ASD-D group there was no significant difference in both LA and RA deformation properties when compared with control subjects. SR imaging indexes could provide new, noninvasive, clinically relevant insight on regional changes in atrial function for patients with ASD. ASD percutaneous closure is useful not only because it is less expensive and invasive than open-heart operation but also for its conservation of both LA and RA regional myocardial properties. FAU - Di Salvo, Giovanni AU - Di Salvo G AD - Physiopathology of the Cardio-Respiratory System and Associated Biotechnologies, Second University of Naples, Naples, Italy. giodisal@yahoo.it FAU - Drago, Manuela AU - Drago M FAU - Pacileo, Giuseppe AU - Pacileo G FAU - Rea, Alessandra AU - Rea A FAU - Carrozza, Marianna AU - Carrozza M FAU - Santoro, Giuseppe AU - Santoro G FAU - Bigazzi, Maurizio Cappelli AU - Bigazzi MC FAU - Caso, Pio AU - Caso P FAU - Russo, Maria Giovanna AU - Russo MG FAU - Carminati, Mario AU - Carminati M FAU - Calabro', Raffaele AU - Calabro' R LA - eng PT - Journal Article PT - Randomized Controlled Trial PL - United States TA - J Am Soc Echocardiogr JT - Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography JID - 8801388 SB - IM MH - *Atrial Function MH - Cardiac Surgical Procedures/*methods MH - Child MH - Echocardiography/*methods MH - Heart Atria/diagnostic imaging MH - Heart Septal Defects, Atrial/complications/*diagnostic imaging/*surgery MH - Humans MH - Stress, Mechanical MH - Treatment Outcome MH - Ventricular Dysfunction, Left/*diagnostic imaging/etiology/*prevention & control EDAT- 2005/09/13 09:00 MHDA- 2006/04/12 09:00 CRDT- 2005/09/13 09:00 PHST- 2004/11/04 00:00 [received] PHST- 2005/09/13 09:00 [pubmed] PHST- 2006/04/12 09:00 [medline] PHST- 2005/09/13 09:00 [entrez] AID - S0894-7317(05)00119-7 [pii] AID - 10.1016/j.echo.2005.01.029 [doi] PST - ppublish SO - J Am Soc Echocardiogr. 2005 Sep;18(9):930-3. doi: 10.1016/j.echo.2005.01.029.