PMID- 16155817
OWN - NLM
STAT- MEDLINE
DCOM- 20051025
LR  - 20131121
IS  - 1139-9287 (Print)
IS  - 1139-9287 (Linking)
VI  - 33
IP  - 5
DP  - 2005 Sep-Oct
TI  - MDMA and serotonin: based on two cases.
PG  - 339-42
AB  - 3,4-methylenedioxyamphetamine (MDMA) or "ecstasy" damages serotonin neurons in 
      all animal species and there is growing evidence that this finding also applies 
      to humans. This fact, together with the increasing extended use in the young 
      population, has important repercussions in the appearance of specific 
      psychopathologic and cognitive disturbances associated to its use. The authors 
      present two clinical cases, in which psychopathological and cognitive symptoms 
      are detected in MDMA users that support this hypothesis. Problems in the 
      diagnosis of psychiatric disorders associated to MDMA and its clinical and 
      therapeutic implications are discussed.
FAU - Garcia Cabeza, I
AU  - Garcia Cabeza I
AD  - Hospital General Universitario Gregorio Maranon, Servicio de Psiquiatria I, Ibiza 
      43, 28009 Madrid, Spain.
FAU - Zabala, A
AU  - Zabala A
FAU - Soto-Montenegro, M L
AU  - Soto-Montenegro ML
FAU - Arango, C
AU  - Arango C
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Spain
TA  - Actas Esp Psiquiatr
JT  - Actas espanolas de psiquiatria
JID - 100886502
RN  - 0 (Hallucinogens)
RN  - 333DO1RDJY (Serotonin)
RN  - KE1SEN21RM (N-Methyl-3,4-methylenedioxyamphetamine)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Amphetamine-Related Disorders/*complications
MH  - Brain/*drug effects/metabolism
MH  - *Hallucinogens/adverse effects
MH  - Humans
MH  - Male
MH  - *N-Methyl-3,4-methylenedioxyamphetamine/adverse effects
MH  - Psychoses, Substance-Induced/*etiology/*metabolism
MH  - Serotonin/*metabolism
EDAT- 2005/09/13 09:00
MHDA- 2005/10/26 09:00
CRDT- 2005/09/13 09:00
PHST- 2005/09/13 09:00 [pubmed]
PHST- 2005/10/26 09:00 [medline]
PHST- 2005/09/13 09:00 [entrez]
AID - 511105110 [pii]
PST - ppublish
SO  - Actas Esp Psiquiatr. 2005 Sep-Oct;33(5):339-42.