PMID- 16176397 OWN - NLM STAT- MEDLINE DCOM- 20060406 LR - 20080528 IS - 0905-6157 (Print) IS - 0905-6157 (Linking) VI - 16 IP - 6 DP - 2005 Sep TI - The prevalence of peanut sensitization and the association to pollen sensitization in a cohort of unselected adolescents--The Odense Adolescence Cohort Study on Atopic Diseases and Dermatitis (TOACS). PG - 501-6 AB - In the last decade an increased occurrence of peanut hypersensitivity and severe anaphylactic reactions to peanut have been reported. However, few prevalence studies have been performed in unselected populations. This study evaluated the point prevalence of peanut hypersensitivity in Danish adolescents. The point prevalence of peanut allergy confirmed by oral challenge was estimated to 0.5%. The number of adolescents sensitized to peanut by specific immunoglobulin E (IgE) (CAP FEIA) and skin prick test (SPT) were higher (5.8% resp. 3.4%). In adolescents without clinically relevant peanut sensitization most cases were sensitized to grass pollen and the IgE class for grass was higher than for peanut. A correlation between peanut and pollen (grass) sensitization is therefore plausible. Before a positive SPT or specific IgE measurement to peanut is considered clinically relevant in a patient, the case history should be evaluated together with examination for pollen sensitization. FAU - Mortz, Charlotte Gotthard AU - Mortz CG AD - Department of Dermatology, Odense University Hospital, Odense C, Denmark. mortz@allergi.sdu.dk FAU - Andersen, Klaus Ejner AU - Andersen KE FAU - Bindslev-Jensen, Carsten AU - Bindslev-Jensen C LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - England TA - Pediatr Allergy Immunol JT - Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology JID - 9106718 RN - 37341-29-0 (Immunoglobulin E) SB - IM MH - Adolescent MH - Antibody Specificity MH - Asthma/complications/epidemiology MH - Case-Control Studies MH - Cohort Studies MH - Cross-Sectional Studies MH - Denmark/epidemiology MH - Dermatitis, Atopic/complications/*epidemiology/immunology MH - Female MH - Follow-Up Studies MH - Humans MH - *Immunization MH - Immunoglobulin E/blood MH - Male MH - Peanut Hypersensitivity/complications/*epidemiology/immunology MH - Prevalence MH - Rhinitis, Allergic, Perennial/complications/epidemiology MH - Rhinitis, Allergic, Seasonal/complications/*epidemiology/immunology MH - Skin Tests EDAT- 2005/09/24 09:00 MHDA- 2006/04/07 09:00 CRDT- 2005/09/24 09:00 PHST- 2005/09/24 09:00 [pubmed] PHST- 2006/04/07 09:00 [medline] PHST- 2005/09/24 09:00 [entrez] AID - PAI302 [pii] AID - 10.1111/j.1399-3038.2005.00302.x [doi] PST - ppublish SO - Pediatr Allergy Immunol. 2005 Sep;16(6):501-6. doi: 10.1111/j.1399-3038.2005.00302.x.