PMID- 16185329
OWN - NLM
STAT- MEDLINE
DCOM- 20051220
LR  - 20221207
IS  - 0001-2815 (Print)
IS  - 0001-2815 (Linking)
VI  - 66
IP  - 4
DP  - 2005 Oct
TI  - Human leukocyte antigen class I and II haplotypes and risk of cervical cancer.
PG  - 321-4
AB  - Human leukocyte antigen (HLA) variations may affect immune response to human 
      papillomavirus infection and subsequent cervical neoplasia risk. We investigated 
      the frequency and relationship between HLA-A-B and HLA-A-B-DR haplotypes among 
      women with cervical cancer/high-grade lesions (n=365) and cytologically normal 
      population controls (n=681) within three cervical neoplasia studies in the US and 
      Costa Rica. Notable differences in haplotype frequencies were observed; the 
      HLA-A*01-B*08 haplotype occurred in >5% of US Caucasians but in <1% of Costa 
      Ricans. The most prevalent HLA-A*24-B*40-DR*04 haplotype in Costa Rica (5%) was 
      found in <1% of US Caucasians. No HLA haplotype was significantly associated with 
      cervical neoplasia, suggesting that individual allele associations reported to 
      date (e.g. HLA-DR*13) are not likely explained by underlying haplotypes.
FAU - Carreon, J D
AU  - Carreon JD
AD  - Division of Cancer Epidemiology and Genetics, National Cancer Institute, 
      Bethesda, MD 20892, USA.
FAU - Martin, M P
AU  - Martin MP
FAU - Hildesheim, A
AU  - Hildesheim A
FAU - Gao, X
AU  - Gao X
FAU - Schiffman, M
AU  - Schiffman M
FAU - Herrero, R
AU  - Herrero R
FAU - Bratti, M C
AU  - Bratti MC
FAU - Sherman, M E
AU  - Sherman ME
FAU - Zaino, R J
AU  - Zaino RJ
FAU - Carrington, M
AU  - Carrington M
FAU - Wang, S S
AU  - Wang SS
LA  - eng
PT  - Journal Article
PL  - England
TA  - Tissue Antigens
JT  - Tissue antigens
JID - 0331072
RN  - 0 (HLA Antigens)
SB  - IM
MH  - Costa Rica
MH  - Female
MH  - Genetic Predisposition to Disease/genetics
MH  - HLA Antigens/*genetics/immunology
MH  - Haplotypes/*genetics/immunology
MH  - Humans
MH  - Papillomaviridae/immunology
MH  - Papillomavirus Infections/genetics/immunology
MH  - Risk Factors
MH  - United States
MH  - Uterine Cervical Neoplasms/*genetics/immunology/virology
MH  - Uterine Cervical Dysplasia/*genetics/immunology/virology
EDAT- 2005/09/28 09:00
MHDA- 2005/12/21 09:00
CRDT- 2005/09/28 09:00
PHST- 2005/09/28 09:00 [pubmed]
PHST- 2005/12/21 09:00 [medline]
PHST- 2005/09/28 09:00 [entrez]
AID - TAN478 [pii]
AID - 10.1111/j.1399-0039.2005.00478.x [doi]
PST - ppublish
SO  - Tissue Antigens. 2005 Oct;66(4):321-4. doi: 10.1111/j.1399-0039.2005.00478.x.