PMID- 16189636
OWN - NLM
STAT- MEDLINE
DCOM- 20051223
LR  - 20181113
IS  - 1342-1751 (Print)
IS  - 1342-1751 (Linking)
VI  - 9
IP  - 3
DP  - 2005 Sep
TI  - Microscopic polyangiitis after silicone breast implantation.
PG  - 252-4
AB  - We describe the case of a patient who developed microscopic polyangiitis (MPA) 
      after silicone breast implantation. A 60-year-old woman who had undergone 
      silicone breast implantation was admitted to our hospital with complaints of 
      general malaise and hematoproteinuria. She was diagnosed as having MPA with 
      evidence of acute progressive renal failure, pulmonary hemorrhage, and positivity 
      for myeloperoxidase-antineutrophil cytoplasmic antibody (ANCA). A renal biopsy 
      showed severe necrotizing and crescentic glomerulonephritis with arteriolitis. 
      The patient received high-dose steroids and plasma exchange treatment, but died 
      of progressive pulmonary hemorrhage and multiple cerebral hemorrhage. Silicone 
      implantation is associated with scleroderma, systemic lupus erythematosus, and 
      rheumatoid arthritis. This case report indicates the possibility of the 
      development of MPA after silicone breast implantation.
FAU - Iyoda, Masayuki
AU  - Iyoda M
AD  - Department of Nephrology, Showa University School of Medicine, 1-5-8 Hatanodai, 
      Shinagawa-ku, Tokyo, 142-8666, Japan, iyoda@med.showa-u.ac.jp
FAU - Ito, Jyun
AU  - Ito J
FAU - Nagai, Hisako
AU  - Nagai H
FAU - Sato, Kasumi
AU  - Sato K
FAU - Kuroki, Aki
AU  - Kuroki A
FAU - Shibata, Takanori
AU  - Shibata T
FAU - Kitazawa, Kozo
AU  - Kitazawa K
FAU - Sugisaki, Tetsuzo
AU  - Sugisaki T
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - Japan
TA  - Clin Exp Nephrol
JT  - Clinical and experimental nephrology
JID - 9709923
RN  - 0 (Silicone Gels)
SB  - IM
MH  - Acute Kidney Injury/*etiology
MH  - Breast Implantation/*adverse effects
MH  - Fatal Outcome
MH  - Female
MH  - Glomerulonephritis/etiology/pathology
MH  - Humans
MH  - Middle Aged
MH  - Silicone Gels
MH  - Vasculitis/*etiology/pathology
EDAT- 2005/09/29 09:00
MHDA- 2005/12/24 09:00
CRDT- 2005/09/29 09:00
PHST- 2004/12/21 00:00 [received]
PHST- 2005/05/06 00:00 [accepted]
PHST- 2005/09/29 09:00 [pubmed]
PHST- 2005/12/24 09:00 [medline]
PHST- 2005/09/29 09:00 [entrez]
AID - 10.1007/s10157-005-0366-7 [doi]
PST - ppublish
SO  - Clin Exp Nephrol. 2005 Sep;9(3):252-4. doi: 10.1007/s10157-005-0366-7.