PMID- 16194019 OWN - NLM STAT- MEDLINE DCOM- 20051220 LR - 20130520 IS - 1426-9686 (Print) IS - 1426-9686 (Linking) VI - 19 IP - 109 DP - 2005 Jul TI - [Value of ST-segment elevation resolution after primary coronary angioplasty in predicting early and late left ventricular function in patients with anterior acute myocardial infarction]. PG - 16-9 AB - The aim of our study was to define a predictive value of ST-segment resolution after coronary reperfusion for early and late left ventricular (LV) function. We also studied its relation to angiographic marker of myocardial reperfusion, myocardial blush grade (MBG). MATERIALS AND METHODS: Study population consisted of 105 patients (75 men, 30 women, mean age 62+/-13 years) treated with primary PTCA for anterior myocardial infarction (AMI) within 12 hours from symptoms onset. ECG was performed before - and 30 min. after PTCA. We evaluated angiographic markers of recanalization (TIMI, corrected TIMI frame count) and myocardial reperfusion - MBG. Echocardiography was performed 3 days and 6 months after AMI. Patients were divided into 2 groups regarding reduction -50% in ST segment elevation after recanalization (rST): group I (n=37) with rST, and group 2 (n=68) without rST RESULTS: In group I we noticed higher CPK level (2890,2+/-2404,2 U/I vs. 3980,9+/-2812,2 U/I, p<0,01). MB grade 3 was significantly more often found in group 1 at 29 pts (78,4%) than in group 2 at 18 pts (23,5%), p<0,0001. MG grade 0 or 1 were more often in group 2 (57,3% vs. 2,7%, p<0,01). Ejection fraction (EF) was higher in group 1 after 3 days (48,9+/-9,5% vs. 44,2+/-14,3%, p<0,01), as well as after 6 months (56,4+/-14,4% vs. 49,5+/-14,3%, p=0,001). After 6 months end-diastolic volume (EDV) was higher in group 2 (128,1+/-46,1 ml vs. 110,2+/-49,7 ml, p<0,008). CONCLUSIONS: ST-resolution after successful PTCA is a simple and effective marker of myocardial reperfusion after recanalization which correlates with angiographic markers of tissue reperfusion. Early ST-segment resolution is connected with better early and late LV function. Patients without early ST-segment elevation resolution have a higher risk of LV remodelling. FAU - Araszkiewicz, Aleksander AU - Araszkiewicz A AD - I Klinika Kardiologii Akademii Medycznej w Poznaniu. aaraszkiewicz@interia.pl FAU - Lesiak, Maciej AU - Lesiak M FAU - Grajek, Stefan AU - Grajek S FAU - Mularek-Kubzdela, Tatiana AU - Mularek-Kubzdela T FAU - Popiel, Malgorzata AU - Popiel M FAU - Cieslinski, Andrzej AU - Cieslinski A LA - pol PT - English Abstract PT - Journal Article TT - Normalizacja uniesien odcinka ST a funkcja lewej komory w okresie wczesnym i odleglym u chorych z zawalem serca sciany przedniej leczonych pierwotna angioplastyka wiencowa. PL - Poland TA - Pol Merkur Lekarski JT - Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego JID - 9705469 SB - IM MH - Aged MH - *Angioplasty, Balloon, Coronary MH - Electrocardiography MH - Female MH - Heart Conduction System/*physiopathology MH - Humans MH - Male MH - Middle Aged MH - Myocardial Infarction/*complications/physiopathology/therapy MH - Predictive Value of Tests MH - Stroke Volume MH - Time Factors MH - Ventricular Dysfunction, Left/*diagnosis/*etiology/physiopathology MH - Ventricular Remodeling EDAT- 2005/10/01 09:00 MHDA- 2005/12/21 09:00 CRDT- 2005/10/01 09:00 PHST- 2005/10/01 09:00 [pubmed] PHST- 2005/12/21 09:00 [medline] PHST- 2005/10/01 09:00 [entrez] PST - ppublish SO - Pol Merkur Lekarski. 2005 Jul;19(109):16-9.