PMID- 16194019
OWN - NLM
STAT- MEDLINE
DCOM- 20051220
LR  - 20130520
IS  - 1426-9686 (Print)
IS  - 1426-9686 (Linking)
VI  - 19
IP  - 109
DP  - 2005 Jul
TI  - [Value of ST-segment elevation resolution after primary coronary angioplasty in
      predicting early and late left ventricular function in patients with anterior
      acute myocardial infarction].
PG  - 16-9
AB  - UNLABELLED: The aim of our study was to define a predictive value of ST-segment
      resolution after coronary reperfusion for early and late left ventricular (LV)
      function. We also studied its relation to angiographic marker of myocardial
      reperfusion, myocardial blush grade (MBG). MATERIALS AND METHODS: Study
      population consisted of 105 patients (75 men, 30 women, mean age 62+/-13 years)
      treated with primary PTCA for anterior myocardial infarction (AMI) within 12
      hours from symptoms onset. ECG was performed before - and 30 min. after PTCA. We 
      evaluated angiographic markers of recanalization (TIMI, corrected TIMI frame
      count) and myocardial reperfusion - MBG. Echocardiography was performed 3 days
      and 6 months after AMI. Patients were divided into 2 groups regarding reduction
      -50% in ST segment elevation after recanalization (rST): group I (n=37) with rST,
      and group 2 (n=68) without rST RESULTS: In group I we noticed higher CPK level
      (2890,2+/-2404,2 U/I vs. 3980,9+/-2812,2 U/I, p<0,01). MB grade 3 was
      significantly more often found in group 1 at 29 pts (78,4%) than in group 2 at 18
      pts (23,5%), p<0,0001. MG grade 0 or 1 were more often in group 2 (57,3% vs.
      2,7%, p<0,01). Ejection fraction (EF) was higher in group 1 after 3 days
      (48,9+/-9,5% vs. 44,2+/-14,3%, p<0,01), as well as after 6 months (56,4+/-14,4%
      vs. 49,5+/-14,3%, p=0,001). After 6 months end-diastolic volume (EDV) was higher 
      in group 2 (128,1+/-46,1 ml vs. 110,2+/-49,7 ml, p<0,008). CONCLUSIONS:
      ST-resolution after successful PTCA is a simple and effective marker of
      myocardial reperfusion after recanalization which correlates with angiographic
      markers of tissue reperfusion. Early ST-segment resolution is connected with
      better early and late LV function. Patients without early ST-segment elevation
      resolution have a higher risk of LV remodelling.
FAU - Araszkiewicz, Aleksander
AU  - Araszkiewicz A
AD  - I Klinika Kardiologii Akademii Medycznej w Poznaniu. aaraszkiewicz@interia.pl
FAU - Lesiak, Maciej
AU  - Lesiak M
FAU - Grajek, Stefan
AU  - Grajek S
FAU - Mularek-Kubzdela, Tatiana
AU  - Mularek-Kubzdela T
FAU - Popiel, Malgorzata
AU  - Popiel M
FAU - Cieslinski, Andrzej
AU  - Cieslinski A
LA  - pol
PT  - English Abstract
PT  - Journal Article
TT  - Normalizacja uniesien odcinka ST a funkcja lewej komory w okresie wczesnym i
      odleglym u chorych z zawalem serca sciany przedniej leczonych pierwotna
      angioplastyka wiencowa.
PL  - Poland
TA  - Pol Merkur Lekarski
JT  - Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego
JID - 9705469
SB  - IM
MH  - Aged
MH  - *Angioplasty, Balloon, Coronary
MH  - Electrocardiography
MH  - Female
MH  - Heart Conduction System/*physiopathology
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Myocardial Infarction/*complications/physiopathology/therapy
MH  - Predictive Value of Tests
MH  - Stroke Volume
MH  - Time Factors
MH  - Ventricular Dysfunction, Left/*diagnosis/*etiology/physiopathology
MH  - Ventricular Remodeling
EDAT- 2005/10/01 09:00
MHDA- 2005/12/21 09:00
CRDT- 2005/10/01 09:00
PHST- 2005/10/01 09:00 [pubmed]
PHST- 2005/12/21 09:00 [medline]
PHST- 2005/10/01 09:00 [entrez]
PST - ppublish
SO  - Pol Merkur Lekarski. 2005 Jul;19(109):16-9.