PMID- 16197963
OWN - NLM
STAT- MEDLINE
DCOM- 20061109
LR  - 20060421
IS  - 0022-5193 (Print)
IS  - 0022-5193 (Linking)
VI  - 240
IP  - 1
DP  - 2006 May 7
TI  - Fuzzy KNN for predicting membrane protein types from pseudo-amino acid 
      composition.
PG  - 9-13
AB  - Cell membranes are vitally important to the life of a cell. Although the basic 
      structure of biological membrane is provided by the lipid bilayer, membrane 
      proteins perform most of the specific functions. Membrane proteins are putatively 
      classified into five different types. Identification of their types is currently 
      an important topic in bioinformatics and proteomics. In this paper, based on the 
      concept of representing protein samples in terms of their pseudo-amino acid 
      composition, the fuzzy K-nearest neighbors (KNN) algorithm has been introduced to 
      predict membrane protein types, and high success rates were observed. It is 
      anticipated that, the current approach, which is based on a branch of fuzzy 
      mathematics and represents a new strategy, may play an important complementary 
      role to the existing methods in this area. The novel approach may also have 
      notable impact on prediction of the other attributes, such as protein structural 
      class, protein subcellular localization, and enzyme family class, among many 
      others.
FAU - Shen, Hong-Bin
AU  - Shen HB
AD  - Institute of Image Processing and Pattern Recognition, Shanghai Jiaotong 
      University, 200030 Shanghai, China.
FAU - Yang, Jie
AU  - Yang J
FAU - Chou, Kuo-Chen
AU  - Chou KC
LA  - eng
PT  - Journal Article
DEP - 20050928
PL  - England
TA  - J Theor Biol
JT  - Journal of theoretical biology
JID - 0376342
RN  - 0 (Amino Acids)
RN  - 0 (Membrane Proteins)
SB  - IM
MH  - Algorithms
MH  - Amino Acids/*analysis
MH  - Fuzzy Logic
MH  - Membrane Proteins/*analysis/classification
MH  - *Models, Chemical
MH  - Sequence Analysis, Protein/methods
EDAT- 2005/10/04 09:00
MHDA- 2006/11/11 09:00
CRDT- 2005/10/04 09:00
PHST- 2005/07/13 00:00 [received]
PHST- 2005/08/15 00:00 [revised]
PHST- 2005/08/18 00:00 [accepted]
PHST- 2005/10/04 09:00 [pubmed]
PHST- 2006/11/11 09:00 [medline]
PHST- 2005/10/04 09:00 [entrez]
AID - S0022-5193(05)00356-5 [pii]
AID - 10.1016/j.jtbi.2005.08.016 [doi]
PST - ppublish
SO  - J Theor Biol. 2006 May 7;240(1):9-13. doi: 10.1016/j.jtbi.2005.08.016. Epub 2005 
      Sep 28.