PMID- 16198210
OWN - NLM
STAT- MEDLINE
DCOM- 20051215
LR  - 20051003
IS  - 0387-7604 (Print)
IS  - 0387-7604 (Linking)
VI  - 27
IP  - 7
DP  - 2005 Oct
TI  - Infantile bilateral striatal necrosis associated with human herpes virus-6 
      (HHV-6) infection.
PG  - 527-30
AB  - A 1-year-old female with acute bilateral striatal necrosis secondary to exanthema 
      subitum associated with human herpesvirus 6 (HHV-6) infection is reported. The 
      patient was previously healthy. She presented with progressive neurologic signs 
      of oral dyskinesia and involuntary movements, after suffering from exanthema 
      subitum. Initial magnetic resonance imaging (MRI) demonstrated abnormal signals 
      in the bilateral striatal regions. In addition, the serum HHV-6 IgM class 
      antibody level was significantly increased. The patient is thought to be the 
      first case of HHV-6 infection related infantile bilateral striatal necrosis 
      (IBSN).
FAU - Murakami, Aki
AU  - Murakami A
AD  - Department of Pediatrics, Kyoto Prefectural University of Medicine, 
      Kawaramachi-Horikoji, Kamigyo, Kyoto 602-8566, Japan. akkylin@koto.kpu-m.ac.jp
FAU - Morimoto, Masafumi
AU  - Morimoto M
FAU - Adachi, Shinsuke
AU  - Adachi S
FAU - Ishimaru, Yosuke
AU  - Ishimaru Y
FAU - Sugimoto, Tohru
AU  - Sugimoto T
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - Netherlands
TA  - Brain Dev
JT  - Brain & development
JID - 7909235
SB  - IM
MH  - *Basal Ganglia Diseases/pathology/physiopathology/virology
MH  - *Corpus Striatum/pathology/physiopathology/virology
MH  - Female
MH  - *Herpesviridae Infections/pathology/physiopathology/virology
MH  - Herpesvirus 6, Human/*metabolism
MH  - Humans
MH  - Infant
MH  - Magnetic Resonance Imaging
MH  - Necrosis/*pathology
EDAT- 2005/10/04 09:00
MHDA- 2005/12/16 09:00
CRDT- 2005/10/04 09:00
PHST- 2004/07/07 00:00 [received]
PHST- 2004/12/10 00:00 [revised]
PHST- 2004/12/10 00:00 [accepted]
PHST- 2005/10/04 09:00 [pubmed]
PHST- 2005/12/16 09:00 [medline]
PHST- 2005/10/04 09:00 [entrez]
AID - S0387-7604(05)00007-0 [pii]
AID - 10.1016/j.braindev.2004.12.004 [doi]
PST - ppublish
SO  - Brain Dev. 2005 Oct;27(7):527-30. doi: 10.1016/j.braindev.2004.12.004.