PMID- 16200833
OWN - NLM
STAT- MEDLINE
DCOM- 20110404
LR  - 20140625
VI  - 19
IP  - 13
DP  - 2005 Jul
TI  - [Study on the association among total immunoglobulin E and eosinophil in nasal 
      polyp].
PG  - 602-4
AB  - OBJECTIVE: To explore the expression of total immunoglobulin E(IgE) and 
      eosinophil in nasal polyp and their roles in the pathogenesis of nasal polyp. 
      METHOD: Thirty eight patients with nasal polyp and 15 control cases were chosen. 
      All samples were stained with Chromotrope 2R histochemical and SP 
      immunohistochemical method separately to examine eosinophil and total IgE+ cells 
      in nasal polyp. RESULT: (1) The level of total IgE and eosinophil in nasal polyp 
      was all significantly higher than that in normal control specimens (P < 0.01). 
      (2) The positive correlation of total IgE and eosinophil was significant (r = 
      0.843, P < 0.01). CONCLUSION: Nasal polyp is a disease characterized by 
      eosinophils infiltration. Type I allergic reaction mediated by IgE assemble and 
      activate eosinophils which may play an important role in the infiltration 
      pathogenesis of nasal polyp.
FAU - Zhu, Shenghua
AU  - Zhu S
AD  - Department of Otolaryngology, Shaoyang Central Hospital, Shaoyang, 422000, China. 
      wuminman@sina.com
FAU - Luo, Xuemei
AU  - Luo X
LA  - chi
PT  - English Abstract
PT  - Journal Article
PL  - China
TA  - Lin Chuang Er Bi Yan Hou Ke Za Zhi
JT  - Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology
JID - 9426080
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Case-Control Studies
MH  - Eosinophils/immunology/*metabolism
MH  - Female
MH  - Humans
MH  - Immunoglobulin E/immunology/*metabolism
MH  - Male
MH  - Middle Aged
MH  - Nasal Mucosa/immunology/metabolism
MH  - Nasal Polyps/immunology/*metabolism/pathology
MH  - Young Adult
EDAT- 2005/10/05 09:00
MHDA- 2011/04/05 06:00
CRDT- 2005/10/05 09:00
PHST- 2005/10/05 09:00 [pubmed]
PHST- 2011/04/05 06:00 [medline]
PHST- 2005/10/05 09:00 [entrez]
PST - ppublish
SO  - Lin Chuang Er Bi Yan Hou Ke Za Zhi. 2005 Jul;19(13):602-4.