PMID- 16208602
OWN - NLM
STAT- MEDLINE
DCOM- 20051031
LR  - 20131121
IS  - 0012-0472 (Print)
IS  - 0012-0472 (Linking)
VI  - 130
IP  - 40
DP  - 2005 Oct 7
TI  - [Diagnosis and therapy of weakly-acid/non-acidic gastroesophageal reflux 
      disease].
PG  - 2266-9
AB  - The therapy of gastroesophageal reflux disease (GERD) is uncomplicated in most 
      cases. However, 20 % of GERD patients suffer from reflux-associated symptoms 
      under therapy with proton pump inhibitors (PPI). The cause of this resistance to 
      PPI-therapy remains unclear. Today, the most discussed theory is the presence of 
      the non- or weakly acidic reflux. Objective measurements of the weakly/non-acidic 
      reflux are available since the development of intraluminal impedance monitoring 
      in combination with pH-monitoring. The therapy of weakly/non-acidic GERD is not 
      well established, so far. In the course of clinical studies the therapeutic 
      spectrum (i. e. modification of the medical therapy, endoscopic anti-reflux 
      procedures or surgical therapy) has to be tested.
FAU - Meining, A
AU  - Meining A
AD  - II. Medizinische Klinik und Poliklinik, Munchen. alexander.meining@lrz.tum.de
FAU - Bajbouj, M
AU  - Bajbouj M
FAU - Stein, H J
AU  - Stein HJ
FAU - Schmid, R M
AU  - Schmid RM
LA  - ger
PT  - English Abstract
PT  - Journal Article
PT  - Review
TT  - Aktuelle Diagnostik und Therapie der schwach sauren/nicht sauren 
      gastroosophagealen Refluxkrankheit.
PL  - Germany
TA  - Dtsch Med Wochenschr
JT  - Deutsche medizinische Wochenschrift (1946)
JID - 0006723
RN  - 0 (GABA Agonists)
RN  - 0 (Proton Pump Inhibitors)
RN  - H789N3FKE8 (Baclofen)
SB  - IM
MH  - Baclofen/therapeutic use
MH  - Electric Impedance
MH  - Esophagoscopy
MH  - Esophagus/chemistry/physiology
MH  - Fundoplication
MH  - GABA Agonists/therapeutic use
MH  - Gastroesophageal Reflux/*diagnosis/*therapy
MH  - Humans
MH  - Hydrogen-Ion Concentration
MH  - Manometry
MH  - Proton Pump Inhibitors
RF  - 16
EDAT- 2005/10/07 09:00
MHDA- 2005/11/01 09:00
CRDT- 2005/10/07 09:00
PHST- 2005/10/07 09:00 [pubmed]
PHST- 2005/11/01 09:00 [medline]
PHST- 2005/10/07 09:00 [entrez]
AID - 10.1055/s-2005-918561 [doi]
PST - ppublish
SO  - Dtsch Med Wochenschr. 2005 Oct 7;130(40):2266-9. doi: 10.1055/s-2005-918561.