PMID- 16212786
OWN - NLM
STAT- MEDLINE
DCOM- 20060123
LR  - 20191210
IS  - 0021-9665 (Print)
IS  - 0021-9665 (Linking)
VI  - 43
IP  - 8
DP  - 2005 Sep
TI  - Validation of an HPLC method for quantitation of MDMA in tablets.
PG  - 434-7
AB  - An isocratic reversed-phase high-performance liquid chromatography (HPLC) method 
      is developed and validated for the quantitation of 
      3,4-methylenedioxymethamphetamine (MDMA) in tablets. The chromatographic 
      separation is achieved with potassium phosphate buffer (pH 3.2)-acetonitrile 
      (9:1, v/v) as mobile phase, a Chromspher B column, and UV detection at 210 nm. 
      The calibration curve is linear from 1.4 to 111 microg/mL. The percent relative 
      standard deviation for intra- and interday precision studies is 2.7% each. The 
      measurement uncertainty is estimated to 9%. The method is specific and 
      successfully used for routine quantitation of MDMA in tablets.
FAU - Muller, I B
AU  - Muller IB
AD  - Department of Forensic Chemistry, University of Copenhagen, Frederik V's Vej 11, 
      2100 Copenhagen, Denmark. Irene.breum@forensic.ku.dk
FAU - Windberg, C N
AU  - Windberg CN
LA  - eng
PT  - Journal Article
PT  - Validation Study
PL  - United States
TA  - J Chromatogr Sci
JT  - Journal of chromatographic science
JID - 0173225
RN  - 0 (Hallucinogens)
RN  - 0 (Tablets)
RN  - KE1SEN21RM (N-Methyl-3,4-methylenedioxyamphetamine)
SB  - IM
MH  - Chromatography, High Pressure Liquid/*methods
MH  - Hallucinogens/*chemistry
MH  - N-Methyl-3,4-methylenedioxyamphetamine/*analysis
MH  - Sensitivity and Specificity
MH  - Tablets/*chemistry
EDAT- 2005/10/11 09:00
MHDA- 2006/01/24 09:00
CRDT- 2005/10/11 09:00
PHST- 2005/10/11 09:00 [pubmed]
PHST- 2006/01/24 09:00 [medline]
PHST- 2005/10/11 09:00 [entrez]
AID - 10.1093/chromsci/43.8.434 [doi]
PST - ppublish
SO  - J Chromatogr Sci. 2005 Sep;43(8):434-7. doi: 10.1093/chromsci/43.8.434.