PMID- 16219147
OWN - NLM
STAT- MEDLINE
DCOM- 20070629
LR  - 20150313
VI  - 24
IP  - 10
DP  - 2005 Oct
TI  - [Expression of S100-labeled dendritic cells in glottic squamous cell carcinoma 
      and its correlation to prognosis].
PG  - 1272-5
AB  - BACKGROUND & OBJECTIVE: Dendritic cells (DCs) are the most important 
      antigen-presenting cells, and can synthesize and secrete S100 protein. This study 
      was designed to investigate the expression of S100-labeled DCs in glottic 
      squamous cell carcinoma, and analyze its correlation to the prognosis. METHODS: 
      The expression of S100-labeled DCs in peritumoral tissues of 111 specimens of 
      gllotic squamous cell carcinoma was detected by immunohistochemistry; 17 
      specimens of normal tissues were used as control. The correlation of S100-labeled 
      DCs expression to prognosis of the 111 patients was evaluated. RESULTS: The 
      positive rates of S100-labeled DCs were 51.35% (57/111) in peritumoral tissues of 
      gllotic squamous cell carcinoma, and 0 in normal tissues. The 5-year survival 
      rate was significantly higher in S100-positive group than in S100-negative group 
      (72.31% vs. 53.91%, P=0.030). CONCLUSIONS: The glottic squamous cell carcinoma 
      patients with obvious infiltration of S100-labeled DCs may achieve good 
      prognosis.
FAU - Chen, Wen-Kuan
AU  - Chen WK
AD  - Key Laboratory of Oncology in Southern China, Guangzhou, Guangdong, P. R. China. 
      chenwenkuan@163.com
FAU - Chen, Fu-Jin
AU  - Chen FJ
FAU - Zeng, Zong-Yuan
AU  - Zeng ZY
FAU - Wu, Guo-Hao
AU  - Wu GH
FAU - Guo, Zhu-Ming
AU  - Guo ZM
FAU - Wei, Mao-Wen
AU  - Wei MW
FAU - Yang, An-Kui
AU  - Yang AK
FAU - Zhang, Quan
AU  - Zhang Q
FAU - He, Jie-Hua
AU  - He JH
FAU - Hou, Jing-Hui
AU  - Hou JH
LA  - chi
PT  - English Abstract
PT  - Journal Article
PL  - China
TA  - Ai Zheng
JT  - Ai zheng = Aizheng = Chinese journal of cancer
JID - 9424852
RN  - 0 (S100 Proteins)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Carcinoma, Squamous Cell/*metabolism/pathology
MH  - Dendritic Cells/*metabolism
MH  - Female
MH  - *Glottis
MH  - Humans
MH  - Immunohistochemistry
MH  - Laryngeal Neoplasms/*metabolism/pathology
MH  - Male
MH  - Middle Aged
MH  - Neoplasm Staging
MH  - Prognosis
MH  - S100 Proteins/*metabolism
MH  - Survival Rate
EDAT- 2005/10/13 09:00
MHDA- 2007/06/30 09:00
CRDT- 2005/10/13 09:00
PHST- 2005/10/13 09:00 [pubmed]
PHST- 2007/06/30 09:00 [medline]
PHST- 2005/10/13 09:00 [entrez]
AID - 1000467X2005101272 [pii]
PST - ppublish
SO  - Ai Zheng. 2005 Oct;24(10):1272-5.