PMID- 16220195
OWN - NLM
STAT- MEDLINE
DCOM- 20131205
LR  - 20051012
IS  - 0371-0874 (Print)
IS  - 0371-0874 (Linking)
VI  - 57
IP  - 5
DP  - 2005 Oct 25
TI  - Characteristic neuronal firing interspike intervals in laterodorsal thalamic 
      nuclei induced by tetanization of rat caudate putamen: possible relations to 
      hippocampal electroencephalogram changes.
PG  - 573-86
AB  - The purpose of the present work was to study the effect of acute tetanization of 
      the right caudate putamen nucleus (ATRC) on single neuronal interspike intervals 
      (ISIs) in both laterodorsal thalamic nuclei (LDi), and electroencephalogram (EEG) 
      wave interpeak intervals (IPIs) in both hippocampi (HPCi). Experiments were 
      performed on 21 male Sprague-Dawley rats weighing 150~250 g. The seizures were 
      induced by the ATRC (60 Hz, 2 s, 0.4~0.6 mA). Quadruple recordings were 
      simultaneously carried out: two for single unit recordings from both LDi, and two 
      for EEG recordings from both HPCi. The ATRC induced: (1) An interactive epileptic 
      electrical network reconstructed in bilateral HPCi, which was driven by primary 
      afterdischarges of single LD neuron. (2) A symmetric mirror-like ISI spot 
      distribution of the LD neuronal firing before and after tetanus. (3) Gradually 
      prolonged LD neuronal discharge intermittence was coherent with synchronous 
      hippocampal EEG activities on the contralateral side. (4) Single LD neuronal 
      spikes were phase- and time-locked to 20~25 Hz gamma oscillations in 
      contralateral HPC. It suggests a particular temporal code patterning of single LD 
      neuronal firing and its relationships to hippocampal EEG wave code in time 
      series, the latter implies the LD neuronal encoding mechanisms of ATRC-induced 
      epileptic electrical network in bilateral HPCi.
FAU - Liu, Qing
AU  - Liu Q
AD  - Departments of Physiology, School of Medicine, Wuhan University, Wuhan 430071, 
      China.
FAU - Han, Dan
AU  - Han D
FAU - Wang, Sheng
AU  - Wang S
FAU - Zou, Zu-Yu
AU  - Zou ZY
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - China
TA  - Sheng Li Xue Bao
JT  - Sheng li xue bao : [Acta physiologica Sinica]
JID - 20730130R
SB  - IM
MH  - Action Potentials/physiology
MH  - Animals
MH  - Caudate Nucleus/*physiology
MH  - Electric Stimulation/methods
MH  - *Electroencephalography
MH  - Epilepsy/etiology/physiopathology
MH  - Hippocampus/*physiology
MH  - Lateral Thalamic Nuclei/*physiology
MH  - Male
MH  - Nerve Net/*physiology
MH  - Neurons/physiology
MH  - Rats
MH  - Rats, Sprague-Dawley
MH  - Reaction Time/physiology
EDAT- 2005/10/13 09:00
MHDA- 2013/12/16 06:00
CRDT- 2005/10/13 09:00
PHST- 2005/10/13 09:00 [pubmed]
PHST- 2013/12/16 06:00 [medline]
PHST- 2005/10/13 09:00 [entrez]
PST - ppublish
SO  - Sheng Li Xue Bao. 2005 Oct 25;57(5):573-86.