PMID- 16235175
OWN - NLM
STAT- MEDLINE
DCOM- 20060131
LR  - 20200403
IS  - 0022-1899 (Print)
IS  - 1537-6613 (Electronic)
IS  - 0022-1899 (Linking)
VI  - 192
IP  - 10
DP  - 2005 Nov 15
TI  - Human coronavirus NL63 is not detected in the respiratory tracts of children with 
      acute Kawasaki disease.
PG  - 1767-71
AB  - Kawasaki disease (KD) is a self-limited, systemic vasculitis of children for 
      which an infectious trigger is suspected. Recently, an association between KD and 
      human coronavirus (HCoV)-New Haven (NH) was reported, on the basis of polymerase 
      chain reaction (PCR) with primers that also amplified HCoV-NL63. We investigated 
      the possible association between these HCoVs in the respiratory tract and KD by 
      reverse-transcriptase (RT) PCR and viral culture in a geographically and 
      ethnically diverse population. Only 1 (2%) of 48 patients with acute KD was 
      positive by RT-PCR for HCoV-NL63/NH in a nasopharyngeal swab. These data do not 
      support an association between these HCoVs and KD.
FAU - Shimizu, Chisato
AU  - Shimizu C
AD  - Department of Pediatrics, University of California, San Diego, School of 
      Medicine, La Jolla, 92093, USA.
FAU - Shike, Hiroko
AU  - Shike H
FAU - Baker, Susan C
AU  - Baker SC
FAU - Garcia, Francesca
AU  - Garcia F
FAU - van der Hoek, Lia
AU  - van der Hoek L
FAU - Kuijpers, Taco W
AU  - Kuijpers TW
FAU - Reed, Sharon L
AU  - Reed SL
FAU - Rowley, Anne H
AU  - Rowley AH
FAU - Shulman, Stanford T
AU  - Shulman ST
FAU - Talbot, Helen K B
AU  - Talbot HK
FAU - Williams, John V
AU  - Williams JV
FAU - Burns, Jane C
AU  - Burns JC
LA  - eng
GR  - HL67011/HL/NHLBI NIH HHS/United States
GR  - K02 HL067011/HL/NHLBI NIH HHS/United States
GR  - R01 HL069413-08/HL/NHLBI NIH HHS/United States
GR  - R01 HL063771/HL/NHLBI NIH HHS/United States
GR  - AI45798/AI/NIAID NIH HHS/United States
GR  - R01 HL069413/HL/NHLBI NIH HHS/United States
GR  - R01 AI045798/AI/NIAID NIH HHS/United States
GR  - R01 HL69413/HL/NHLBI NIH HHS/United States
GR  - HL63771/HL/NHLBI NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
DEP - 20051017
PL  - United States
TA  - J Infect Dis
JT  - The Journal of infectious diseases
JID - 0413675
SB  - IM
MH  - Child
MH  - Child, Preschool
MH  - Coronavirus/genetics/*isolation & purification
MH  - Coronavirus Infections/*complications/*virology
MH  - Female
MH  - Humans
MH  - Infant
MH  - Male
MH  - Mucocutaneous Lymph Node Syndrome/*virology
MH  - Respiratory System/*virology
MH  - Reverse Transcriptase Polymerase Chain Reaction
MH  - Virus Cultivation
PMC - PMC2888540
MID - NIHMS211551
EDAT- 2005/10/20 09:00
MHDA- 2006/02/01 09:00
PMCR- 2005/11/15
CRDT- 2005/10/20 09:00
PHST- 2005/05/06 00:00 [received]
PHST- 2005/06/21 00:00 [accepted]
PHST- 2005/10/20 09:00 [pubmed]
PHST- 2006/02/01 09:00 [medline]
PHST- 2005/10/20 09:00 [entrez]
PHST- 2005/11/15 00:00 [pmc-release]
AID - JID34903 [pii]
AID - 10.1086/497170 [doi]
PST - ppublish
SO  - J Infect Dis. 2005 Nov 15;192(10):1767-71. doi: 10.1086/497170. Epub 2005 Oct 17.