PMID- 16244587
OWN - NLM
STAT- MEDLINE
DCOM- 20051215
LR  - 20100115
IS  - 1812-9269 (Print)
IS  - 1812-9269 (Linking)
VI  - 27
IP  - 3
DP  - 2005 Sep
TI  - Novel cytogenetic findings revealed by conventional cytogenetic and FISH analyses 
      in leukaemia patients.
PG  - 229-32
AB  - AIM: To describe novel cytogenetic findings in four leukaemia patients. METHODS: 
      Conventional cytogenetic (CC) and fluorescence in situ hybridization (FISH) 
      analyses were performed on bone marrow samples of four leukaemia patients. 
      RESULTS: In this study, t(3;10)(q11;q25) and t(2;22)(p21;q11.2) were detected as 
      novel translocations. t(8;16;21)(q22.1;q13;q22) and 
      t(1;6;9;22)(p36.1;p21.3;q34;q11) were found as variant translocations, and these 
      variant translocations were confirmed by Interphase-FISH and Multi-colour-FISH. 
      CONCLUSION: Newly identified cytogenetic findings can lead us to characterize 
      cytogenetic evolution of the haematological malignancies. Further investigations 
      are certainly warranted to resolve the prognostic impact of these new cytogenetic 
      abnormalities.
FAU - Karauzum, S B
AU  - Karauzum SB
AD  - Department of Medical Biology and Genetics, Faculty of Medicine, Akdeniz 
      University, Antalya, Turkey. sibelkaruzum@akdeniz.edu.tr
FAU - Bilgen, T
AU  - Bilgen T
FAU - Karadogan, I
AU  - Karadogan I
FAU - Yakut, S
AU  - Yakut S
FAU - Cetin, Z
AU  - Cetin Z
FAU - Ugur, A
AU  - Ugur A
FAU - Luleci, G
AU  - Luleci G
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Ukraine
TA  - Exp Oncol
JT  - Experimental oncology
JID - 101230541
SB  - IM
MH  - Adult
MH  - Aged
MH  - Bone Marrow Cells
MH  - Cytogenetic Analysis
MH  - Female
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Karyotyping
MH  - Leukemia/*genetics
MH  - Male
MH  - Middle Aged
MH  - *Translocation, Genetic
EDAT- 2005/10/26 09:00
MHDA- 2005/12/16 09:00
CRDT- 2005/10/26 09:00
PHST- 2005/10/26 09:00 [pubmed]
PHST- 2005/12/16 09:00 [medline]
PHST- 2005/10/26 09:00 [entrez]
AID - 23/445 [pii]
PST - ppublish
SO  - Exp Oncol. 2005 Sep;27(3):229-32.