PMID- 16249098
OWN - NLM
STAT- MEDLINE
DCOM- 20060526
LR  - 20071115
IS  - 1053-8119 (Print)
IS  - 1053-8119 (Linking)
VI  - 30
IP  - 1
DP  - 2006 Mar
TI  - Neural correlates of regulating negative emotions related to moral violations.
PG  - 313-24
AB  - Previous neuroimaging studies have identified several brain regions associated 
      with regulating emotional responses. Different kinds of emotional stimuli, 
      however, may recruit different regulatory processes and, in turn, recruit 
      different regions. We compared emotion regulation for two types of negative 
      emotional stimuli: those involving moral violations (moral stimuli), and those 
      not involving moral violations (non-moral stimuli). In addition, we investigated 
      whether activation in medial prefrontal cortex (MPFC), a region implicated 
      previously in specifically moral processing, may instead reflect greater social 
      and emotional content. Ten female subjects were scanned using fMRI while they 
      passively viewed or were instructed to decrease emotional reactions to moral and 
      non-moral pictures closely matched on social and emotional content. Passive 
      viewing of both picture types elicited similar activations in areas related to 
      the processing of social and emotional content, including MPFC and amygdala. 
      During regulation, different patterns of activation in these regions were 
      observed for moral vs. non-moral pictures. These results suggest that the neural 
      correlates of regulating emotional reactions are modulated by the emotional 
      content of stimuli, such as moral violations. In addition, the current findings 
      suggest that some brain regions previously implicated in moral processing reflect 
      the processing of greater social and emotional content in moral stimuli.
FAU - Harenski, Carla L
AU  - Harenski CL
AD  - Department of Psychology, Emory University, 532 North Kilgo Circle, Atlanta, GA 
      30322, USA.
FAU - Hamann, Stephan
AU  - Hamann S
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, Non-P.H.S.
DEP - 20051024
PL  - United States
TA  - Neuroimage
JT  - NeuroImage
JID - 9215515
SB  - IM
MH  - Adaptation, Psychological/physiology
MH  - Adult
MH  - Affect/*physiology
MH  - Amygdala/*physiology
MH  - Arousal/*physiology
MH  - Brain Mapping
MH  - Cerebral Cortex/physiology
MH  - Female
MH  - Humans
MH  - *Image Processing, Computer-Assisted
MH  - *Imaging, Three-Dimensional
MH  - *Magnetic Resonance Imaging
MH  - *Morals
MH  - Nerve Net/physiology
MH  - Personality Inventory
MH  - Prefrontal Cortex/*physiology
MH  - Statistics as Topic
MH  - Visual Perception/*physiology
EDAT- 2005/10/27 09:00
MHDA- 2006/05/27 09:00
CRDT- 2005/10/27 09:00
PHST- 2005/02/21 00:00 [received]
PHST- 2005/09/07 00:00 [revised]
PHST- 2005/09/14 00:00 [accepted]
PHST- 2005/10/27 09:00 [pubmed]
PHST- 2006/05/27 09:00 [medline]
PHST- 2005/10/27 09:00 [entrez]
AID - S1053-8119(05)00718-4 [pii]
AID - 10.1016/j.neuroimage.2005.09.034 [doi]
PST - ppublish
SO  - Neuroimage. 2006 Mar;30(1):313-24. doi: 10.1016/j.neuroimage.2005.09.034. Epub 
      2005 Oct 24.