PMID- 16263546
OWN - NLM
STAT- MEDLINE
DCOM- 20060124
LR  - 20220321
IS  - 0144-3615 (Print)
IS  - 0144-3615 (Linking)
VI  - 25
IP  - 7
DP  - 2005 Oct
TI  - Primary fallopian tube carcinoma - the experience of a UK cancer centre and a 
      review of the literature.
PG  - 694-702
AB  - Primary fallopian tube carcinoma (PFTC) is rare but may be under-diagnosed. We 
      have analysed the incidence, clinical findings and outcome in patients with PFTC 
      at the RUH Gynaecological Cancer Centre in Bath between 1999 and 2004, and 
      compared the incidence with that of advanced ovarian carcinoma (OC). Eight 
      patients had PFTC, seven of whom were diagnosed after 2001, and 55 patients had 
      advanced OC. Our data suggest a relative increase in the number of patients with 
      PFTC over the study period. PFTC patients had a mean age of 69.6 years, most 
      presented with postmenopausal bleeding, two had a second carcinoma, three were 
      nulliparous and none were diagnosed pre-operatively. All were treated surgically 
      and received platinum-based chemotherapy. Although PFTC patients had better 
      outcomes than those with advanced OC, the difference was not statistically 
      significant (p = 0.088). Accurate diagnosis and differentiation of PFTC from 
      advanced OC are important for monitoring trends in incidence, for better 
      characterisation of prognostic features and improved management.
FAU - Clayton, N L
AU  - Clayton NL
AD  - Department of Obstetrics and Gynaecology, University of Bristol, UK.
FAU - Jaaback, K S
AU  - Jaaback KS
FAU - Hirschowitz, L
AU  - Hirschowitz L
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Review
PL  - England
TA  - J Obstet Gynaecol
JT  - Journal of obstetrics and gynaecology : the journal of the Institute of 
      Obstetrics and Gynaecology
JID - 8309140
SB  - IM
MH  - Age Distribution
MH  - Aged
MH  - Aged, 80 and over
MH  - Biopsy, Needle
MH  - Cancer Care Facilities
MH  - Carcinoma/*epidemiology/*pathology/therapy
MH  - Chemotherapy, Adjuvant
MH  - Combined Modality Therapy
MH  - Fallopian Tube Neoplasms/*epidemiology/*pathology/therapy
MH  - Fallopian Tubes/*surgery
MH  - Female
MH  - Humans
MH  - Immunohistochemistry
MH  - Incidence
MH  - Middle Aged
MH  - Neoplasm Staging
MH  - Radiotherapy, Adjuvant
MH  - Retrospective Studies
MH  - Survival Rate
MH  - Treatment Outcome
MH  - United Kingdom/epidemiology
RF  - 42
EDAT- 2005/11/03 09:00
MHDA- 2006/01/25 09:00
CRDT- 2005/11/03 09:00
PHST- 2005/11/03 09:00 [pubmed]
PHST- 2006/01/25 09:00 [medline]
PHST- 2005/11/03 09:00 [entrez]
AID - W7P176164G306J60 [pii]
AID - 10.1080/01443610500292395 [doi]
PST - ppublish
SO  - J Obstet Gynaecol. 2005 Oct;25(7):694-702. doi: 10.1080/01443610500292395.