PMID- 16272784
OWN - NLM
STAT- MEDLINE
DCOM- 20060310
LR  - 20191109
IS  - 1349-2365 (Print)
IS  - 1349-2365 (Linking)
VI  - 46
IP  - 5
DP  - 2005 Sep
TI  - Cough reflex by ventricular premature contractions.
PG  - 923-6
AB  - A 72-year-old man was referred for further assessment of a chronic cough. He 
      noticed an association between the episodes of coughing and palpitations. 
      Electrocardiography (ECG) revealed normal sinus rhythm and sporadic unifocal 
      ventricular premature contractions (VPCs). Each cough was preceded by a premature 
      beat. Continuous wave Doppler echocardiography revealed a VPC-induced transient 
      increase in the pulmonary artery blood flow. He was successfully treated for VPCs 
      with oral disopyramide, resulting in subsidence of both the coughing and 
      palpitations. We suspect that the VPC-induced hemodynamic changes in the 
      pulmonary circulation might be responsible for coughing in our patient. Premature 
      contractions should be considered as a possible cause of chronic dry cough in the 
      clinical setting.
FAU - Niimi, Akio
AU  - Niimi A
AD  - Division of Respiratory Medicine, Kyoto University Hospital, Japan.
FAU - Kihara, Yasuki
AU  - Kihara Y
FAU - Sumita, Yoshiyuki
AU  - Sumita Y
FAU - Okano, Yoshiaki
AU  - Okano Y
FAU - Tambara, Keiichi
AU  - Tambara K
FAU - Fujita, Masatoshi
AU  - Fujita M
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - Japan
TA  - Int Heart J
JT  - International heart journal
JID - 101244240
RN  - 0 (Anti-Arrhythmia Agents)
RN  - GFO928U8MQ (Disopyramide)
SB  - IM
MH  - Anti-Arrhythmia Agents/therapeutic use
MH  - Chronic Disease
MH  - Cough/*etiology
MH  - Disopyramide/therapeutic use
MH  - Echocardiography, Doppler
MH  - *Electrocardiography
MH  - Heart Rate
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Ventricular Premature Complexes/*complications/*diagnosis/drug therapy
EDAT- 2005/11/08 09:00
MHDA- 2006/03/11 09:00
CRDT- 2005/11/08 09:00
PHST- 2005/11/08 09:00 [pubmed]
PHST- 2006/03/11 09:00 [medline]
PHST- 2005/11/08 09:00 [entrez]
AID - JST.JSTAGE/ihj/46.923 [pii]
AID - 10.1536/ihj.46.923 [doi]
PST - ppublish
SO  - Int Heart J. 2005 Sep;46(5):923-6. doi: 10.1536/ihj.46.923.