PMID- 16272809
OWN - NLM
STAT- MEDLINE
DCOM- 20060203
LR  - 20191210
IS  - 0031-6903 (Print)
IS  - 0031-6903 (Linking)
VI  - 125
IP  - 11
DP  - 2005 Nov
TI  - [Examination of rheumatoid factor and other serum markers in rheumatoid 
      arthritis].
PG  - 881-7
AB  - Rheumatoid factor (IgM-RF) has been widely used to diagnose rheumatoid arthritis 
      (RA) in clinical practice. We investigated the RA diagnostic performances of 
      anti-cyclic citrullinated peptide antibody (anti-CCP), matrix metalloproteinase-3 
      (MMP-3), anti-agalactosyl IgG antibody (CA*RF), and anti-calpastatin antibody 
      (ACA) in comparison with IgM-RF. Among 68 RA patients, IgM-RF was positive in 31 
      (45.6%) and negative in 37 (54.4%). In the IgM-RF-positive group, positivity in 
      anti-CCP, CA*RF, and ACA was 97%, 100%, and 97%, respectively, although that in 
      MMP-3 (74%) was inferior to the others. On the other hand, in the IgM-RF-negative 
      group, positivity in anti-CCP, MMP-3, and ACA was 73%, 81%, and 86%, 
      respectively, although that in CA*RF was only 59%. We conclude that the 
      combination of IgM-RF and anti-CCP/ACA will provide an accurate diagnosis of RA 
      in clinical practice.
FAU - Hiura, Kazuya
AU  - Hiura K
AD  - Obihiro Kosei Hospital, Japan.
FAU - Iwaki-Egawa, Sachiko
AU  - Iwaki-Egawa S
FAU - Matsuno, Hiroaki
AU  - Matsuno H
FAU - Watanabe, Yasuhiro
AU  - Watanabe Y
LA  - jpn
PT  - Comparative Study
PT  - Evaluation Study
PT  - Journal Article
PL  - Japan
TA  - Yakugaku Zasshi
JT  - Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
JID - 0413613
RN  - 0 (Autoantibodies)
RN  - 0 (Biomarkers)
RN  - 0 (Calcium-Binding Proteins)
RN  - 0 (Immunoglobulin M)
RN  - 0 (Peptides, Cyclic)
RN  - 0 (cyclic citrullinated peptide)
RN  - 79079-11-1 (calpastatin)
RN  - 9009-79-4 (Rheumatoid Factor)
SB  - IM
MH  - Arthritis, Rheumatoid/*diagnosis
MH  - Autoantibodies/*blood
MH  - Biomarkers/blood
MH  - Calcium-Binding Proteins/*immunology
MH  - Humans
MH  - Immunoglobulin M/*blood
MH  - Peptides, Cyclic/*immunology
MH  - Rheumatoid Factor/*blood
EDAT- 2005/11/08 09:00
MHDA- 2006/02/04 09:00
CRDT- 2005/11/08 09:00
PHST- 2005/11/08 09:00 [pubmed]
PHST- 2006/02/04 09:00 [medline]
PHST- 2005/11/08 09:00 [entrez]
AID - JST.JSTAGE/yakushi/125.881 [pii]
AID - 10.1248/yakushi.125.881 [doi]
PST - ppublish
SO  - Yakugaku Zasshi. 2005 Nov;125(11):881-7. doi: 10.1248/yakushi.125.881.