PMID- 16278644
OWN - NLM
STAT- MEDLINE
DCOM- 20060119
LR  - 20161026
IS  - 0021-9509 (Print)
IS  - 0021-9509 (Linking)
VI  - 46
IP  - 5
DP  - 2005 Oct
TI  - Late outcome and perioperative complications for surgery of locally recurrent 
      bronchogenic carcinoma.
PG  - 515-8
AB  - AIM: Many doubts involve a 2(nd) surgical approach for local relapse of non small 
      cell lung cancer (NSCLC) since iterative resections represent a well-recognized 
      treatment in second primary lung cancer (SPLC). METHODS: The medical reports of 
      patients who underwent surgical resection, between 1988 and 2002, were reviewed. 
      All patients submitted to 2(nd) operation were examined according to Martini and 
      Melamed criteria to distinguish between local recurrence and second primary lung 
      cancer. RESULTS: Complete resection for NSCLC was performed in 1 386 patients. 
      Nineteen patients were submitted to surgery for local recurrence (17 men and 2 
      women) and mean age at the time of 1(st) operation was 61 years (range 41-78 
      years). The 1(st) operation consisted of lobectomy in 15 cases, anatomical 
      segmentectomy in 2 and wedge resection in 2. The 2(nd) pulmonary resection was 
      completion pneumonectomy in 16 cases, completion lobectomy in 2, wedge resection 
      in 1. Major complications occurred in 26% and overall hospital mortality was 5%. 
      Five-year survival after 2(nd) intervention was 31% and median survival 27 
      months. Survival was better when the time between 1(st) resection and cancer 
      relapse was longer than 14 months and when recurrence was intrapulmonary. 
      CONCLUSIONS: A new malignant lesion can be operated if it is solitary and 
      intrapulmonary, if accurate staging is negative and if the patient is able to go 
      through 2(nd) surgery from cardiopulmonary evaluation.
FAU - Campione, A
AU  - Campione A
AD  - Department of Thoracic and Cardiovascular Surgery, Thoracic Surgery Unit, 
      University Hospital of Siena, Siena, Italy. campioneandrea@libero.it
FAU - Ligabue, T
AU  - Ligabue T
FAU - Luzzi, L
AU  - Luzzi L
FAU - Ghiribelli, C
AU  - Ghiribelli C
FAU - Paladini, P
AU  - Paladini P
FAU - Voltolini, L
AU  - Voltolini L
FAU - Di Bisceglie, M
AU  - Di Bisceglie M
FAU - D'Agata, A
AU  - D'Agata A
FAU - Gotti, G
AU  - Gotti G
LA  - eng
PT  - Journal Article
PL  - Italy
TA  - J Cardiovasc Surg (Torino)
JT  - The Journal of cardiovascular surgery
JID - 0066127
SB  - IM
MH  - Adult
MH  - Aged
MH  - Carcinoma, Bronchogenic/mortality/*surgery
MH  - Carcinoma, Non-Small-Cell Lung/mortality/*surgery
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Lung Neoplasms/mortality/*surgery
MH  - Male
MH  - Middle Aged
MH  - Neoplasm Recurrence, Local/mortality/*surgery
MH  - Pneumonectomy/*adverse effects
MH  - Reoperation/adverse effects
MH  - Retrospective Studies
MH  - Survival Rate
MH  - Treatment Outcome
EDAT- 2005/11/10 09:00
MHDA- 2006/01/20 09:00
CRDT- 2005/11/10 09:00
PHST- 2005/11/10 09:00 [pubmed]
PHST- 2006/01/20 09:00 [medline]
PHST- 2005/11/10 09:00 [entrez]
PST - ppublish
SO  - J Cardiovasc Surg (Torino). 2005 Oct;46(5):515-8.