PMID- 16281091
OWN - NLM
STAT- MEDLINE
DCOM- 20060113
LR  - 20061115
IS  - 1008-682X (Print)
IS  - 1008-682X (Linking)
VI  - 7
IP  - 4
DP  - 2005 Dec
TI  - Significant reduction of sperm disomy in six men: effect of traditional Chinese 
      medicine?
PG  - 419-25
AB  - AIM: To test the hypothesis that levels of sperm disomy fell significantly in six 
      men treated by traditional Chinese medicine (TCM). METHODS: Fluorescence in situ 
      hybridization (FISH) was done on the sperm heads of six men before and during 
      treatment by TCM. RESULTS: There was a significant reduction in sperm disomy in 
      all six men. This coincided with TCM treatment. CONCLUSION: This is the first 
      study reporting a significant reduction in sperm disomy in men over a given time 
      course. The fact that this coincided with TCM treatment is intriguing but no 
      conclusions can be drawn from this until placebo-controlled clinical trials are 
      implemented.
FAU - Tempest, Helen G
AU  - Tempest HG
AD  - Department of Biosciences, University of Kent, Canterbury CT2 7NJ, UK.
FAU - Homa, Sheryl T
AU  - Homa ST
FAU - Zhai, Xiao-Ping
AU  - Zhai XP
FAU - Griffin, Darren K
AU  - Griffin DK
LA  - eng
PT  - Comparative Study
PT  - Controlled Clinical Trial
PT  - Journal Article
PL  - China
TA  - Asian J Androl
JT  - Asian journal of andrology
JID - 100942132
RN  - 0 (Drugs, Chinese Herbal)
SB  - IM
MH  - Adult
MH  - Aneuploidy
MH  - Chromosomes, Human, X/genetics
MH  - Chromosomes, Human, Y/genetics
MH  - Drugs, Chinese Herbal/*administration & dosage
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Infertility, Male/*drug therapy/genetics/*pathology
MH  - Male
MH  - *Medicine, Chinese Traditional
MH  - Spermatozoa/*pathology/physiology
MH  - Treatment Outcome
EDAT- 2005/11/11 09:00
MHDA- 2006/01/18 09:00
CRDT- 2005/11/11 09:00
PHST- 2005/11/11 09:00 [pubmed]
PHST- 2006/01/18 09:00 [medline]
PHST- 2005/11/11 09:00 [entrez]
AID - 10.1111/j.1745-7262.2005.00068.x [doi]
PST - ppublish
SO  - Asian J Androl. 2005 Dec;7(4):419-25. doi: 10.1111/j.1745-7262.2005.00068.x.