PMID- 16282436
OWN - NLM
STAT- MEDLINE
DCOM- 20060420
LR  - 20131121
IS  - 8750-7587 (Print)
IS  - 0161-7567 (Linking)
VI  - 100
IP  - 3
DP  - 2006 Mar
TI  - Exogenous carbohydrate oxidation rates are elevated after combined ingestion of 
      glucose and fructose during exercise in the heat.
PG  - 807-16
AB  - The first purpose of this study was to investigate whether a glucose 
      (GLU)+fructose (FRUC) beverage would result in a higher exogenous carbohydrate 
      (CHO) oxidation rate and a higher fluid availability during exercise in the heat 
      compared with an isoenergetic GLU beverage. A second aim of the study was to 
      examine whether ingestion of GLU at a rate of 1.5 g/min during exercise in the 
      heat would lead to a reduced muscle glycogen oxidation rate compared with 
      ingestion of water (WAT). Eight trained male cyclists (maximal oxygen uptake: 
      64+/-1 ml.kg-1.min-1) cycled on three different occasions for 120 min at 50% 
      maximum power output at an ambient temperature of 31.9+/-0.1 degrees C. Subjects 
      received, in random order, a solution providing either 1.5 g/min of GLU, 1.0 
      g/min of GLU+0.5 g/min of FRUC, or WAT. Exogenous CHO oxidation during the last 
      hour of exercise was approximately 36% higher (P<0.05) in GLU+FRUC compared with 
      GLU, and peak oxidation rates were 1.14+/-0.05 and 0.77+/-0.08 g/min, 
      respectively. Endogenous CHO oxidation was significantly lower (P<0.05) in 
      GLU+FRUC compared with WAT. Muscle glycogen oxidation was not different after 
      ingestion of GLU or WAT. Plasma deuterium enrichments were significantly higher 
      (P<0.05) in WAT and GLU+FRUC compared with GLU. Furthermore, at 60 and 75 min of 
      exercise, plasma deuterium enrichments were higher (P<0.05) in WAT compared with 
      GLU+FRUC. Ingestion of GLU+FRUC during exercise in the heat resulted in higher 
      exogenous CHO oxidation rates and fluid availability compared with ingestion of 
      GLU and reduced endogenous CHO oxidation compared with ingestion of WAT.
FAU - Jentjens, Roy L P G
AU  - Jentjens RL
AD  - Human Performance Labaratory, School of Sport and Exercise Sciences, Univ. of 
      Birmingham, Edgbaston, B15 2TT, Birmingham, UK.
FAU - Underwood, Katie
AU  - Underwood K
FAU - Achten, Juul
AU  - Achten J
FAU - Currell, Kevin
AU  - Currell K
FAU - Mann, Christopher H
AU  - Mann CH
FAU - Jeukendrup, Asker E
AU  - Jeukendrup AE
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
DEP - 20051110
PL  - United States
TA  - J Appl Physiol (1985)
JT  - Journal of applied physiology (Bethesda, Md. : 1985)
JID - 8502536
RN  - 0 (Blood Glucose)
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Fats)
RN  - 0 (Lactates)
RN  - 142M471B3J (Carbon Dioxide)
RN  - 30237-26-4 (Fructose)
RN  - 9005-79-2 (Glycogen)
RN  - AR09D82C7G (Deuterium)
RN  - IY9XDZ35W2 (Glucose)
SB  - IM
MH  - Adult
MH  - Blood Glucose/analysis
MH  - Body Temperature/physiology
MH  - Carbon Dioxide/metabolism
MH  - Deuterium/blood
MH  - Dietary Carbohydrates/administration & dosage/*metabolism
MH  - Drinking/physiology
MH  - Exercise/*physiology
MH  - Fats/metabolism
MH  - Fructose/administration & dosage/*metabolism
MH  - Glucose/administration & dosage/*metabolism
MH  - Glycogen/metabolism
MH  - *Hot Temperature
MH  - Humans
MH  - Lactates/blood
MH  - Male
MH  - Muscle, Skeletal/metabolism
MH  - Osmolar Concentration
MH  - Oxidation-Reduction
MH  - Pulmonary Ventilation/physiology
MH  - Respiration
MH  - Time Factors
MH  - Water-Electrolyte Balance
EDAT- 2005/11/12 09:00
MHDA- 2006/04/21 09:00
CRDT- 2005/11/12 09:00
PHST- 2005/11/12 09:00 [pubmed]
PHST- 2006/04/21 09:00 [medline]
PHST- 2005/11/12 09:00 [entrez]
AID - 00322.2005 [pii]
AID - 10.1152/japplphysiol.00322.2005 [doi]
PST - ppublish
SO  - J Appl Physiol (1985). 2006 Mar;100(3):807-16. doi: 
      10.1152/japplphysiol.00322.2005. Epub 2005 Nov 10.