PMID- 16285894
OWN - NLM
STAT- MEDLINE
DCOM- 20060209
LR  - 20051115
IS  - 1672-7681 (Print)
IS  - 1672-7681 (Linking)
VI  - 1
IP  - 5
DP  - 2004 Oct
TI  - Dendritic cells as vectors for immunotherapy of tumor and its application for 
      gastric cancer therapy.
PG  - 351-6
AB  - Dendritic cells (DCs) are recognized as the most potent antigen-presenting cells 
      (APCs) with the ability to stimulate naive resting T cells and initiate primary 
      immune responses. DCs are poised to capture antigen (Ag), migrate to draining 
      lymphoid organs, and, after a process of maturation, select Ag-specific 
      lymphocytes to which they present the processed Ag, thereby inducing immune 
      responses. Numerous studies indicated that immunotherapies utilizing 
      DC-presenting tumor-associated antigens can safely be administered to cancer 
      patients and induce significant immunologic and clinical responses. Moreover, it 
      has been demonstrated that DCs are related to clinical stage, invasion, 
      metastasis and prognosis of gastric cancer. DC-based tumor vaccines become a new 
      effective immunoadjuvant therapy for gastric cancer.
FAU - Wu, Yugang
AU  - Wu Y
AD  - Department of General Surgery, the First Affiliated Hospital of Soochow 
      University, Suzhou, Jiangsu 215006, China.
FAU - Wang, Liang
AU  - Wang L
FAU - Zhang, Yanyun
AU  - Zhang Y
LA  - eng
PT  - Journal Article
PT  - Review
PL  - China
TA  - Cell Mol Immunol
JT  - Cellular & molecular immunology
JID - 101242872
RN  - 0 (Antigens, Neoplasm)
SB  - IM
MH  - Animals
MH  - Antigen Presentation/*immunology
MH  - Antigens, Neoplasm/*immunology
MH  - Chemotherapy, Adjuvant
MH  - Dendritic Cells/immunology/*transplantation
MH  - Humans
MH  - *Immunotherapy, Adoptive
MH  - Stomach Neoplasms/immunology/*therapy
MH  - T-Lymphocytes/*immunology
RF  - 62
EDAT- 2005/11/16 09:00
MHDA- 2006/02/10 09:00
CRDT- 2005/11/16 09:00
PHST- 2005/11/16 09:00 [pubmed]
PHST- 2006/02/10 09:00 [medline]
PHST- 2005/11/16 09:00 [entrez]
PST - ppublish
SO  - Cell Mol Immunol. 2004 Oct;1(5):351-6.