PMID- 16286670
OWN - NLM
STAT- MEDLINE
DCOM- 20060126
LR  - 20191109
IS  - 1526-484X (Print)
IS  - 1526-484X (Linking)
VI  - 15
IP  - 4
DP  - 2005 Aug
TI  - Effects of acute versus chronic L-carnitine L-tartrate supplementation on 
      metabolic responses to steady state exercise in males and females.
PG  - 386-400
AB  - Twelve healthy active subjects (6 male, 6 female) performed 60 min of exercise 
      (60% VO(2max)) on 3 occasions after supplementing with L-Carnitine L-tartrate 
      (LCLT) or placebo. Each subject received a chronic dose, an acute dose, and 
      placebo in a randomized, double-blind crossover design. Dietary intake and 
      exercise were replicated for 2 d prior to each trial. In males there was a 
      significant difference in rate of carbohydrate (CHO) oxidation between placebo 
      and chronic trials (P = 0.02) but not placebo and acute trials (P = 0.70), and 
      total CHO oxidation was greater following chronic supplementation vs. placebo 
      )mean +/- standard deviation) of 93.8 (17.3) g/hr and 78.2 (23.3) g/h, 
      respectively). In females, no difference in rate of, or total, CHO oxidation was 
      observed between trials. No effects on fat oxidation or hematological responses 
      were noted in either gender group. Under these experimental conditions, chronic 
      LCLT supplementation increased CHO oxidation in males during exercise but this 
      was not observed in females.
FAU - Abramowicz, Weronika N
AU  - Abramowicz WN
AD  - Dept of Sports Studies, University of Stirling, Stirling, Scotland.
FAU - Galloway, Stuart D R
AU  - Galloway SD
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
PL  - United States
TA  - Int J Sport Nutr Exerc Metab
JT  - International journal of sport nutrition and exercise metabolism
JID - 100939812
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Tartrates)
RN  - 12001-76-2 (Vitamin B Complex)
RN  - S7UI8SM58A (Carnitine)
SB  - IM
MH  - Adult
MH  - Carnitine/*administration & dosage/pharmacokinetics
MH  - Cross-Over Studies
MH  - Dietary Carbohydrates/*metabolism
MH  - Dietary Supplements
MH  - Double-Blind Method
MH  - Drug Administration Schedule
MH  - Energy Metabolism/*drug effects/physiology
MH  - Exercise/*physiology
MH  - Female
MH  - Humans
MH  - Male
MH  - Oxidation-Reduction
MH  - Oxygen Consumption/physiology
MH  - Sex Factors
MH  - Tartrates/*administration & dosage/pharmacokinetics
MH  - Vitamin B Complex/*administration & dosage/pharmacokinetics
EDAT- 2005/11/16 09:00
MHDA- 2006/01/27 09:00
CRDT- 2005/11/16 09:00
PHST- 2005/11/16 09:00 [pubmed]
PHST- 2006/01/27 09:00 [medline]
PHST- 2005/11/16 09:00 [entrez]
AID - 10.1123/ijsnem.15.4.386 [doi]
PST - ppublish
SO  - Int J Sport Nutr Exerc Metab. 2005 Aug;15(4):386-400. doi: 
      10.1123/ijsnem.15.4.386.