PMID- 16287081
OWN - NLM
STAT- MEDLINE
DCOM- 20060331
LR  - 20070813
IS  - 1097-0134 (Electronic)
IS  - 0887-3585 (Linking)
VI  - 62
IP  - 1
DP  - 2006 Jan 1
TI  - Managing and mining protein crystallization data.
PG  - 4-7
AB  - The crystallization of macromolecules remains a major bottleneck in structural 
      biology. The routine screening of more than one thousand crystallization 
      conditions and subsequent optimization by fine screening presents a challenge to 
      conventional laboratory notebook keeping. In addition, the development of 
      high-throughput robotic crystallization and imaging systems presents a pressing 
      need for low-cost laboratory information management system (LIMS). Here we 
      describe CLIMS2, a crystallization LIMS that features a simple, user-friendly 
      graphical interface, allowing the storage, management, retrieval and mining of 
      crystallization data. The CLIMS2 executable and documentation is freely available 
      at http://clims.med.monash.edu.au.
CI  - 2005 Wiley-Liss, Inc.
FAU - Amin, Abdullah A
AU  - Amin AA
AD  - Victorian Bioinformatics Consortium, Monash University, Clayton, Victoria, 
      Australia.
FAU - Faux, Noel G
AU  - Faux NG
FAU - Fenalti, Gustavo
AU  - Fenalti G
FAU - Williams, Geoffrey
AU  - Williams G
FAU - Bernadou, Adam
AU  - Bernadou A
FAU - Daglish, Ben
AU  - Daglish B
FAU - Keefe, Karen
AU  - Keefe K
FAU - Middleton, Shayne
AU  - Middleton S
FAU - Rae, Joseph
AU  - Rae J
FAU - Tetis, Kosmas
AU  - Tetis K
FAU - Law, Ruby H P
AU  - Law RH
FAU - Fulton, Kate F
AU  - Fulton KF
FAU - Rossjohn, Jamie
AU  - Rossjohn J
FAU - Whisstock, James C
AU  - Whisstock JC
FAU - Buckle, Ashley M
AU  - Buckle AM
LA  - eng
GR  - Wellcome Trust/United Kingdom
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Proteins
JT  - Proteins
JID - 8700181
RN  - 0 (Macromolecular Substances)
RN  - 0 (Proteins)
SB  - IM
MH  - Computer Graphics
MH  - Crystallization
MH  - Databases, Protein
MH  - Information Systems
MH  - Macromolecular Substances/chemistry
MH  - Proteins/*chemistry/isolation & purification
EDAT- 2005/11/16 09:00
MHDA- 2006/04/01 09:00
CRDT- 2005/11/16 09:00
PHST- 2005/11/16 09:00 [pubmed]
PHST- 2006/04/01 09:00 [medline]
PHST- 2005/11/16 09:00 [entrez]
AID - 10.1002/prot.20776 [doi]
PST - ppublish
SO  - Proteins. 2006 Jan 1;62(1):4-7. doi: 10.1002/prot.20776.