PMID- 16295136
OWN - NLM
STAT- MEDLINE
DCOM- 20151201
LR  - 20191109
IS  - 1610-0379 (Print)
IS  - 1610-0379 (Linking)
VI  - 1
IP  - 6
DP  - 2003 Jun
TI  - The role of dendritic cells during infection.
PG  - 438-42
AB  - The skin and the mucosa of the respiratory and gastrointestinal tracts are 
      continuously exposed to microorganisms, but only a limited number of these enter 
      the body and cause disease. To resist microbial infection, the host has developed 
      a multitude of defense mechanisms involving the innate and adaptive immune 
      systems. Dendritic cells (DCs) provide the link between these arms of the immune 
      system. The initiation of an immune response is critically dependent on the 
      activation of DCs, which can discriminate between different classes of 
      microorganisms and elicit tailored antimicrobial immune responses. They have an 
      extraordinary capacity to stimulate naive T cells and initiate primary immune 
      responses. In turn, some pathogens interfere with DC function to block or delay 
      their elimination by the host. Progress in understanding the role of DCs in the 
      host response to microbes is reviewed.
FAU - Kolb-Maurer, Annette
AU  - Kolb-Maurer A
AD  - Universitats-Hautklinik Wurzburg, Germany. ankolb@biozentrum.uni-wuerzburg.de
FAU - Brocker, Eva-B
AU  - Brocker EB
LA  - eng
PT  - Journal Article
PT  - Review
PL  - Germany
TA  - J Dtsch Dermatol Ges
JT  - Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German 
      Society of Dermatology : JDDG
JID - 101164708
RN  - 0 (Cytokines)
SB  - IM
MH  - Adaptive Immunity/*immunology
MH  - Cytokines/physiology
MH  - Dendritic Cells/*immunology
MH  - Humans
MH  - Immune Evasion/immunology
MH  - Immunity, Innate/*immunology
MH  - Microscopy, Electron, Scanning
MH  - Mucous Membrane/immunology
MH  - Phagocytosis/immunology
MH  - Skin Diseases, Bacterial/*immunology
EDAT- 2005/11/22 09:00
MHDA- 2015/12/15 06:00
CRDT- 2005/11/22 09:00
PHST- 2005/11/22 09:00 [pubmed]
PHST- 2015/12/15 06:00 [medline]
PHST- 2005/11/22 09:00 [entrez]
AID - 10.1046/j.1610-0387.2003.03722.x [doi]
PST - ppublish
SO  - J Dtsch Dermatol Ges. 2003 Jun;1(6):438-42. doi: 
      10.1046/j.1610-0387.2003.03722.x.