PMID- 16303699
OWN - NLM
STAT- MEDLINE
DCOM- 20060223
LR  - 20100323
IS  - 0803-5253 (Print)
IS  - 0803-5253 (Linking)
VI  - 94
IP  - 11
DP  - 2005 Nov
TI  - Sensory evoked potentials in infants with Down syndrome.
PG  - 1615-8
AB  - AIM: To investigate the sensory functions of the peripheral to central pathways 
      in infants with Down syndrome (DS) by sensory evoked potentials. METHODS: 
      Fifty-five infants, 30 DS infants and 25 controls, were examined by multimodal 
      evoked potentials, including brainstem auditory evoked potentials (BAEP), visual 
      evoked potentials (VEP) and short-latency somatosensory evoked potentials (SSEP). 
      RESULTS: No obvious difference was found in the peak latencies between the two 
      groups for BAEP. Nine children with DS showed abnormal BAEP; six had hearing loss 
      and three had prolonged wave I latencies. For VEP, the peak latencies of P(2) and 
      N(2) were significantly longer and the amplitudes were smaller in the DS group 
      than in the control group. Of the 30 infants with DS, five had significantly 
      prolonged P(2) latencies and two had lower amplitudes. In SSEP, the mean 
      latencies of N(20) and the interpeak latencies of N(13)-N(20) of the infants with 
      DS showed apparent prolongation compared to the controls. Seven of 30 (23.3%) DS 
      patients had prolonged N(20) latencies. CONCLUSION: Our results indicate that 
      various sensory deficits occur in patients with DS during the first year of life.
FAU - Chen, Yung-Jung
AU  - Chen YJ
AD  - Department of Paediatrics, Medical College, National Cheng Kung University, 
      Tainan, Taiwan. pcyj@mail.ncku.edu.tw
FAU - Fang, Peng-Cheng
AU  - Fang PC
LA  - eng
PT  - Journal Article
PL  - Norway
TA  - Acta Paediatr
JT  - Acta paediatrica (Oslo, Norway : 1992)
JID - 9205968
SB  - IM
MH  - Analysis of Variance
MH  - Case-Control Studies
MH  - Down Syndrome/complications/*physiopathology
MH  - *Evoked Potentials, Auditory, Brain Stem
MH  - *Evoked Potentials, Somatosensory
MH  - *Evoked Potentials, Visual
MH  - Female
MH  - Humans
MH  - Infant
MH  - Male
MH  - Sensation Disorders/etiology/*physiopathology
MH  - Statistics, Nonparametric
EDAT- 2005/11/24 09:00
MHDA- 2006/02/24 09:00
CRDT- 2005/11/24 09:00
PHST- 2005/11/24 09:00 [pubmed]
PHST- 2006/02/24 09:00 [medline]
PHST- 2005/11/24 09:00 [entrez]
AID - K71U431L27214463 [pii]
AID - 10.1080/08035250500252609 [doi]
PST - ppublish
SO  - Acta Paediatr. 2005 Nov;94(11):1615-8. doi: 10.1080/08035250500252609.