PMID- 16305687
OWN - NLM
STAT- MEDLINE
DCOM- 20060120
LR  - 20221207
IS  - 0001-2815 (Print)
IS  - 0001-2815 (Linking)
VI  - 66
IP  - 6
DP  - 2005 Dec
TI  - Identification of a new HLA-B allele, HLA-B*4443, in a German family.
PG  - 696-9
AB  - A novel human leukocyte antigen (HLA)-B allele is described. The allele was 
      identified in a German blood donor of Caucasian origin. Because high-resolution 
      HLA-typing using sequence-specific primers gave inconclusive results, 
      sequence-based typing was performed. Nucleotide sequences of exons 2 and 3 most 
      closely match with HLA-B*4417 and HLA-B*440301 (99.5% identity). The predicted 
      protein sequence revealed a single amino acid substitution (D156L) compared with 
      the HLA-B*4417 allele but two substitutions (Y113H, D116S) compared with the 
      HLA-B*440301 allele. Therefore, the novel allele has been officially assigned 
      HLA-B*4443 by the WHO Nomenclature Committee. The HLA-B*4443 allele was found 
      with the A*2301, Cw*0401, B*4443, DRB1*0701, DRB4*0107, and DQB1*0202 haplotype.
FAU - Thude, H
AU  - Thude H
AD  - Institute for Transfusion Medicine, University Hospital of Jena, Germany. 
      hansjoerg.thude@med.uni-jena.de
FAU - Hardt, C
AU  - Hardt C
FAU - Schorner, U
AU  - Schorner U
FAU - Ferencik, S
AU  - Ferencik S
FAU - Helfricht, C
AU  - Helfricht C
FAU - Barz, D
AU  - Barz D
LA  - eng
PT  - Journal Article
PL  - England
TA  - Tissue Antigens
JT  - Tissue antigens
JID - 0331072
RN  - 0 (HLA-B Antigens)
SB  - IM
MH  - Alleles
MH  - Amino Acid Sequence
MH  - Amino Acid Substitution
MH  - Base Sequence
MH  - Exons/*genetics
MH  - Female
MH  - Germany
MH  - HLA-B Antigens/*genetics
MH  - Haplotypes/genetics
MH  - Humans
MH  - Male
MH  - Molecular Sequence Data
MH  - Pedigree
MH  - Sequence Homology, Amino Acid
MH  - Sequence Homology, Nucleic Acid
MH  - White People
EDAT- 2005/11/25 09:00
MHDA- 2006/01/21 09:00
CRDT- 2005/11/25 09:00
PHST- 2005/11/25 09:00 [pubmed]
PHST- 2006/01/21 09:00 [medline]
PHST- 2005/11/25 09:00 [entrez]
AID - TAN490 [pii]
AID - 10.1111/j.1399-0039.2005.00490.x [doi]
PST - ppublish
SO  - Tissue Antigens. 2005 Dec;66(6):696-9. doi: 10.1111/j.1399-0039.2005.00490.x.