PMID- 16315784
OWN - NLM
STAT- MEDLINE
DCOM- 20060126
LR  - 20161021
IS  - 1124-0490 (Print)
IS  - 1124-0490 (Linking)
VI  - 22
IP  - 3
DP  - 2005 Oct
TI  - National survey on status of steroid therapy for cardiac sarcoidosis in Japan.
PG  - 210-3
AB  - AIM: This investigation was undertaken to clarify the current status of steroid 
      therapy for cardiac sarcoidosis in Japan. METHODS: A questionnaire survey was 
      conducted throughout Japan concerning cases in which steroid therapy had been 
      administered. Replies describing 52 cases (15 men, 37 women; mean age +/- SD, 
      59.8 +/- 14.5 years) were analyzed. RESULTS: Of the 49 patients whose New York 
      Heart Association (NYHA) functional classification was reported, 29 (55.8%) were 
      in class I; 13 (25.0%) class II; 4 (7.7%) class III and 3 (5.8%) class IV. The 
      most common initial steroid dose (used in 35 cases, or 67.3%) was 30 mg/day or 60 
      mg on alternate days. In most cases (85.4%), this dose was continued for 1 month 
      followed by tapering by 5 mg every 2 to 4 weeks until reaching the maintenance 
      dose of 5 to 10 mg/day. Steroid therapy was reported to result in improvement in 
      54%, no change in 40%, and deterioration in 6%. CONCLUSION: This nationwide 
      questionnaire survey indicated fairly uniform patterns of steroid therapy for 
      cardiac sarcoidosis in Japan, with clinical improvement in over one-half of cases 
      and possible stabilization in most others.
FAU - Hiramitsu, Shinya
AU  - Hiramitsu S
AD  - Division of Cardiology, Department of Internal Medicine, Fujita Health University 
      School of Medicine, Toyoake, Japan.
FAU - Morimoto, Shin-ichiro
AU  - Morimoto S
FAU - Uemura, Akihisa
AU  - Uemura A
FAU - Kato, Yasuchika
AU  - Kato Y
FAU - Kimura, Katsutomo
AU  - Kimura K
FAU - Ohtsuki, Masatsugu
AU  - Ohtsuki M
FAU - Kato, Shigeru
AU  - Kato S
FAU - Sugiura, Atsushi
AU  - Sugiura A
FAU - Miyagishima, Kenji
AU  - Miyagishima K
FAU - Hishida, Hitoshi
AU  - Hishida H
FAU - Sugisaki, Katsunori
AU  - Sugisaki K
FAU - Tsuda, Tomiyasu
AU  - Tsuda T
LA  - eng
PT  - Journal Article
PL  - Italy
TA  - Sarcoidosis Vasc Diffuse Lung Dis
JT  - Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG
JID - 9610928
RN  - 0 (Glucocorticoids)
RN  - 9PHQ9Y1OLM (Prednisolone)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Cardiomyopathies/classification/*drug therapy
MH  - Drug Administration Schedule
MH  - Female
MH  - Glucocorticoids/administration & dosage/therapeutic use
MH  - Health Care Surveys
MH  - Heart Block/etiology
MH  - Humans
MH  - Japan
MH  - Male
MH  - Middle Aged
MH  - Prednisolone/administration & dosage/*therapeutic use
MH  - Sarcoidosis/classification/*drug therapy
EDAT- 2005/12/01 09:00
MHDA- 2006/01/27 09:00
CRDT- 2005/12/01 09:00
PHST- 2005/12/01 09:00 [pubmed]
PHST- 2006/01/27 09:00 [medline]
PHST- 2005/12/01 09:00 [entrez]
PST - ppublish
SO  - Sarcoidosis Vasc Diffuse Lung Dis. 2005 Oct;22(3):210-3.