PMID- 16327533
OWN - NLM
STAT- MEDLINE
DCOM- 20060516
LR  - 20220317
IS  - 0883-9212 (Print)
IS  - 0883-9212 (Linking)
VI  - 25
IP  - 6
DP  - 2005 Nov-Dec
TI  - Minimal clinically important difference for the UCSD Shortness of Breath 
      Questionnaire.
PG  - 370-7
AB  - PURPOSE: A minimal clinically important difference (MCID) is important in 
      evaluating clinical measures such as health-related quality of life (HRQOL) 
      instruments. The purpose of this analysis is to evaluate MCID for the UCSD 
      Shortness of Breath Questionnaire (SOBQ). METHODS: We examined measures of 
      disease-specific and generic HRQOL in 164 subjects with chronic lung disease 
      before and after pulmonary rehabilitation. Subjects completed 2 disease-specific 
      [SOBQ, Chronic Respiratory Questionnaire (CRQ)], and 2 generic HRQOL measures 
      [RAND-36 and Quality of Well-Being Scale (QWB)]. The MCID was calculated using 3 
      methods: effect size, standard error of the measurement (SEM), and comparison 
      between the SOBQ and CRQ Dyspnea scores. RESULTS: HRQOL measures correlated 
      moderately with measures of maximum exercise tolerance but not with lung function 
      (FEV1, FVC). HRQOL and exercise capacity improved significantly after pulmonary 
      rehabilitation. A change of 5 units for the SOBQ appears to be a reasonable MCID 
      for this instrument. The calculated MCIDs for the CRQ (0.47/item) and QWB (0.031) 
      were consistent with established change scores. CONCLUSIONS: The MCID calculated 
      using an SEM approach for the SOBQ, CRQ, and QWB meets clinical expectations for 
      these instruments. HRQOL measures provide information that is complementary and 
      distinct from physiological measures.
FAU - Kupferberg, David H
AU  - Kupferberg DH
AD  - Division of Pulmonary and Critical Care Medicine and Department of Family and 
      Preventive Medicine, University of California, San Diego, USA.
FAU - Kaplan, Robert M
AU  - Kaplan RM
FAU - Slymen, Donald J
AU  - Slymen DJ
FAU - Ries, Andrew L
AU  - Ries AL
LA  - eng
GR  - 1 F32 HL68358-01/HL/NHLBI NIH HHS/United States
GR  - R01 HD/HL 30912/HD/NICHD NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - J Cardiopulm Rehabil
JT  - Journal of cardiopulmonary rehabilitation
JID - 8511296
SB  - IM
MH  - Aged
MH  - Dyspnea/diagnosis/*etiology
MH  - Exercise Tolerance
MH  - Female
MH  - *Health Status
MH  - Humans
MH  - Lung Diseases, Obstructive/*physiopathology
MH  - Male
MH  - *Quality of Life
MH  - Respiratory Function Tests
MH  - *Surveys and Questionnaires
EDAT- 2005/12/06 09:00
MHDA- 2006/05/17 09:00
CRDT- 2005/12/06 09:00
PHST- 2005/12/06 09:00 [pubmed]
PHST- 2006/05/17 09:00 [medline]
PHST- 2005/12/06 09:00 [entrez]
AID - 00008483-200511000-00011 [pii]
AID - 10.1097/00008483-200511000-00011 [doi]
PST - ppublish
SO  - J Cardiopulm Rehabil. 2005 Nov-Dec;25(6):370-7. doi: 
      10.1097/00008483-200511000-00011.