PMID- 16329633 OWN - NLM STAT- MEDLINE DCOM- 20060131 LR - 20161018 IS - 1997-7298 (Print) IS - 1997-7298 (Linking) VI - 105 IP - 11 DP - 2005 TI - [The analysis of brainstem acoustic evoked potentials in diphtheritic polyneuropathy]. PG - 35-8 AB - The possibility of central and peripheral impairment of the acoustic analyser was studied in 18 patients with severe diphtheritic polyneuropathy (DP) using brainstem acoustic evoked potentials (BAEPs). The acoustic nerve impairment was found in 27.8%, the central abnormalities--in 44.4%. All the patients with CNS impairment suffered from chronic alcoholism. The data obtained have been compared to those of 26 patients with chronic alcoholism. In this group, peripheral polyneuropathy was confirmed in 76.9% cases; BAEPs revealed isolated involvement of the peripheral part of the acoustic nerve in 7.7% and CNS impairment was found in 84.6% patients. The results of the study suggest that diphtheritic toxin is not implicated in CNS lesions. Central changes found in the BAEPs analysis were related to chronic alcohol intake and did not aggravate diphtheria course. FAU - Nikitin, S S AU - Nikitin SS FAU - Suopneva, N A AU - Suopneva NA FAU - Fedin, P A AU - Fedin PA FAU - Korepina, O S AU - Korepina OS FAU - Savitskaia, N G AU - Savitskaia NG FAU - Ostafiichuk, A V AU - Ostafiichuk AV FAU - Piradov, M A AU - Piradov MA LA - rus PT - English Abstract PT - Journal Article PL - Russia (Federation) TA - Zh Nevrol Psikhiatr Im S S Korsakova JT - Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova JID - 9712194 SB - IM MH - Adult MH - Alcoholism/complications MH - *Auditory Diseases, Central/diagnosis/etiology/physiopathology MH - Cochlear Nerve/*physiopathology MH - Diphtheria/*complications MH - Evoked Potentials, Auditory, Brain Stem/*physiology MH - Female MH - Humans MH - Male MH - Middle Aged MH - Polyneuropathies/*etiology MH - Severity of Illness Index EDAT- 2005/12/07 09:00 MHDA- 2006/02/01 09:00 CRDT- 2005/12/07 09:00 PHST- 2005/12/07 09:00 [pubmed] PHST- 2006/02/01 09:00 [medline] PHST- 2005/12/07 09:00 [entrez] PST - ppublish SO - Zh Nevrol Psikhiatr Im S S Korsakova. 2005;105(11):35-8.