PMID- 16332382
OWN - NLM
STAT- MEDLINE
DCOM- 20060615
LR  - 20061115
IS  - 0034-5288 (Print)
IS  - 0034-5288 (Linking)
VI  - 81
IP  - 1
DP  - 2006 Aug
TI  - Pathological and aetiological studies of multifocal interstitial nephritis in 
      wasted pigs at slaughter.
PG  - 92-8
AB  - Multifocal interstitial nephritis in pigs has been associated with several 
      infectious agents. The objective of the present study was to investigate several 
      different potential infectious agents associated with "white-spotted" kidneys in 
      pigs suffering from wasting at slaughter (aged 6-8 months). Twenty-nine case 
      kidneys (with a "white-spotted" gross appearance) classified into 3 macroscopic 
      lesional grades, and 15 control kidneys (lacking gross lesions), were obtained 
      from a pig abattoir. Laboratory analyses to detect potential associations with 
      the aforementioned pathological condition with Leptospira spp., porcine 
      circovirus type 2 (PCV2), porcine parvovirus (PPV), porcine reproductive and 
      respiratory syndrome virus (PRRSV), and bacteria, were carried out. 
      Microscopically, interstitial nephritis with a lymphofollicular inflammatory 
      pattern (follicular nephritis) was observed in both case and control kidneys, 
      with a higher frequency seen in the former ones. No leptospires were identified, 
      although antibodies to the Pomona and Bratislava serovars were detected. Some 
      pyogenic bacteria were also isolated from both case and control kidneys. PCV2 
      nucleic acid was only detected in 1 case kidney. PRRSV antigen was not found in 
      any tested sample. Some pigs were tested positive for PPV by serology. 
      Apparently, none of the studied agents were specifically associated as being the 
      potential cause of the renal lesions in the studied wasted pigs. The fact that 
      these chronic lesions may have been the consequence of a previous infection with 
      one of these studied microorganisms, or more, and eventually with other 
      non-tested infectious agents during the growing-finishing period, cannot be ruled 
      out.
FAU - Martinez, J
AU  - Martinez J
AD  - Departmento de Atencion Sanitaria, Salud Publica y Sanidad Animal (Histologia y 
      Anatomia Patologica), Facultad de Ciencias Experimentales y de la Salud, 
      Universidad Cardenal Herrera-CEU, Edificio Seminario, s/n, 46113 Moncada, 
      Valencia, Spain.
FAU - Segales, J
AU  - Segales J
FAU - Aduriz, G
AU  - Aduriz G
FAU - Atxaerandio, R
AU  - Atxaerandio R
FAU - Jaro, P
AU  - Jaro P
FAU - Ortega, J
AU  - Ortega J
FAU - Peris, B
AU  - Peris B
FAU - Corpa, J M
AU  - Corpa JM
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20051205
PL  - England
TA  - Res Vet Sci
JT  - Research in veterinary science
JID - 0401300
SB  - IM
MH  - Abattoirs
MH  - Animals
MH  - Case-Control Studies
MH  - Kidney/microbiology/pathology/virology
MH  - Nephritis, Interstitial/microbiology/*pathology/*veterinary/virology
MH  - Swine
MH  - Swine Diseases/microbiology/*pathology/virology
MH  - Wasting Syndrome/microbiology/*pathology/*veterinary/virology
EDAT- 2005/12/08 09:00
MHDA- 2006/06/16 09:00
CRDT- 2005/12/08 09:00
PHST- 2005/07/26 00:00 [received]
PHST- 2005/10/12 00:00 [revised]
PHST- 2005/10/17 00:00 [accepted]
PHST- 2005/12/08 09:00 [pubmed]
PHST- 2006/06/16 09:00 [medline]
PHST- 2005/12/08 09:00 [entrez]
AID - S0034-5288(05)00201-8 [pii]
AID - 10.1016/j.rvsc.2005.10.005 [doi]
PST - ppublish
SO  - Res Vet Sci. 2006 Aug;81(1):92-8. doi: 10.1016/j.rvsc.2005.10.005. Epub 2005 Dec 
      5.