PMID- 16337813
OWN - NLM
STAT- MEDLINE
DCOM- 20061026
LR  - 20060417
IS  - 1053-8119 (Print)
IS  - 1053-8119 (Linking)
VI  - 30
IP  - 3
DP  - 2006 Apr 15
TI  - Do visual perspective tasks need theory of mind?
PG  - 1059-68
AB  - Reviews [Frith, U., Frith, C.D., 2003. Development and neurophysiology of 
      mentalising. Philos. Trans. R. Soc., B 358, 685-694.] of several imaging studies 
      report robust involvement of medial prefrontal cortex (MPFC) in "theory of mind" 
      (ToM) tasks. Surprisingly, this activation is notably absent when judging another 
      person's visual perspective [Vogeley, K., May, M., Ritzl, A., Falkai, P., Zilles, 
      K., Fink, G.R., 2004. Neural correlates of first-person perspective as one 
      constituent of human self-consciousness. J. Cogn. Neurosci. 16, 817-827.]. The 
      objective of our study was to see whether this activation can be recovered when 
      the difference between what observers see is clearly one of perspectives (in 
      front vs. behind) and not potentially a difference in what observers are looking 
      at. Despite this change, there was still no apparent activation of MPFC. We did 
      find activation in the temporo-parietal junction (TPJ) recently emphasized as 
      centrally involved in processing false belief stories [Saxe, R., Kanwisher, N., 
      2003. People thinking about thinking people: The role of the temporo-parietal 
      junction in "theory of mind". NeuroImage 19, 1835-1842.], which also create a 
      stark contrast of perspectives. By integrating extant neurophysiological evidence 
      on theory of mind processing, we suggest that the dorsal part of the TPJ region 
      is responsible for representing perspective differences and making behavioral 
      predictions, while the more ventral part of TPJ and the MPFC region is 
      responsible for predicting behavioral consequences and the MPFC also emotional 
      consequences of mental states.
FAU - Aichhorn, Markus
AU  - Aichhorn M
AD  - Center of Neurocognitive Research, University of Salzburg, Austria. 
      markus.aichhorn@sbg.ac.at
FAU - Perner, Josef
AU  - Perner J
FAU - Kronbichler, Martin
AU  - Kronbichler M
FAU - Staffen, Wolfgang
AU  - Staffen W
FAU - Ladurner, Gunther
AU  - Ladurner G
LA  - eng
PT  - Journal Article
DEP - 20051206
PL  - United States
TA  - Neuroimage
JT  - NeuroImage
JID - 9215515
SB  - IM
MH  - Adult
MH  - Brain/*physiology
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - *Psychological Theory
MH  - Task Performance and Analysis
MH  - Visual Perception/*physiology
EDAT- 2005/12/13 09:00
MHDA- 2006/10/27 09:00
CRDT- 2005/12/13 09:00
PHST- 2005/07/20 00:00 [received]
PHST- 2005/09/22 00:00 [revised]
PHST- 2005/10/20 00:00 [accepted]
PHST- 2005/12/13 09:00 [pubmed]
PHST- 2006/10/27 09:00 [medline]
PHST- 2005/12/13 09:00 [entrez]
AID - S1053-8119(05)02407-9 [pii]
AID - 10.1016/j.neuroimage.2005.10.026 [doi]
PST - ppublish
SO  - Neuroimage. 2006 Apr 15;30(3):1059-68. doi: 10.1016/j.neuroimage.2005.10.026. 
      Epub 2005 Dec 6.